{
  "abstract": "Background: Coronary artery ectasia (CAE) predisposes to abnormal flow, thrombosis, and adverse cardiovascular outcomes.\n\nCase Summary: A 72-year-old woman with diffuse multivessel CAE, systemic arterial ectasia, and psoriasis presented with inferior ST-segment elevation myocardial infarction in the setting of left bundle branch block. Angiography demonstrated an approximately 8-mm ectatic right coronary artery with complete thrombotic occlusion. Aspiration thrombectomy restored partial flow, but stenting was deferred because of diffuse ectasia, persistent thrombus, and malapposition risk. She was discharged on a direct oral anticoagulant plus single antiplatelet therapy.\n\nDiscussion: Diffuse CAE is a high-risk thrombotic substrate, and ST-segment elevation myocardial infarction management is challenging because of altered flow, large thrombus burden, and percutaneous coronary intervention limitations.\n\nTake-Home Message: Diffuse systemic ectasia warrants individualized antithrombotic therapy and longitudinal imaging surveillance.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Internal Medicine, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA",
    "Department of Cardiology, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA"
  ],
  "article_type": "case report",
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Ahmed Reda Gonnah"
    },
    {
      "affs": [
        1
      ],
      "name": "Fahdem Iamrl"
    },
    {
      "affs": [
        1
      ],
      "name": "Douglas Jacoby"
    },
    {
      "affs": [
        1
      ],
      "name": "Allison L. Tsao"
    },
    {
      "affs": [
        1
      ],
      "name": "Mahesh K. Vidula"
    },
    {
      "affs": [
        1
      ],
      "name": "Daniel E. Soffer"
    },
    {
      "affs": [
        1
      ],
      "name": "Monika Sanghavi"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/9czndqm1c3h7n.bib",
  "cited_by": 0,
  "doi": "10.1016/j.jaccas.2026.110203",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13699021/",
  "id": "9czndqm1c3h7n",
  "issns": [
    "2666-0849"
  ],
  "landing_url": "https://doi.org/10.1016/j.jaccas.2026.110203",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Clinical Case"
    ],
    [
      "heading",
      "Coronary, Peripheral, and Structural Interventions"
    ],
    [
      "lcc",
      "RC666-701"
    ],
    [
      "openalex",
      "2740|Coronary Artery Anomalies"
    ]
  ],
  "openalex": "W7212297229",
  "pdf_url": "https://www.jacc.org/doi/pdf/10.1016/j.jaccas.2026.110203?download=true",
  "pmcid": "PMC13699021",
  "pmid": "42726045",
  "published": "2026-09-11",
  "publisher": "Elsevier",
  "ris": "https://research.draconitic.com/paper/9czndqm1c3h7n.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:42Z",
      "native_id": "PMC13699021",
      "source": "pmc",
      "url": "https://doi.org/10.1016/j.jaccas.2026.110203"
    },
    {
      "first_seen": "2026-10-30T13:43:16Z",
      "native_id": "d28fd1a432f4479795a7b2b992f9eb00",
      "source": "doaj",
      "url": "https://doi.org/10.1016/j.jaccas.2026.110203"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "lcc:RC666-701",
      "subfield": "cardiovascular"
    }
  ],
  "title": "Management of Acute Coronary Syndrome in Severe Diffuse Coronary Artery Ectasia",
  "title_text": "Management of Acute Coronary Syndrome in Severe Diffuse Coronary Artery Ectasia",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:43:16Z",
  "url": "https://research.draconitic.com/paper/9czndqm1c3h7n",
  "venue": "JACC Case Reports",
  "versions": []
}