{
  "abstract": "Polygonatum cyrtonema Hua in Jiuhua Mountain (JHPCH) is a nationally recognized geographically indicated medicinal plant known for its bioactive polysaccharides with diverse pharmacological activities. This study isolated a homogeneous polysaccharide JPCP-70-0 from JHPCH via hot water extraction, ethanol precipitation, and chromatographic purification. Structural characterization by GC-MS, FT-IR, and NMR identified it as a neutral fructan (2.88 × 104 Da) with Glc/Fru (6.65%/93.35%), a backbone of →1)-β-D-Fruf-(2→, and side chains of →6)-β-D-Fruf-(2→). Using Caenorhabditis elegans as a model, we evaluated JPCP-70-0’s effects on nematode growth. Results showed concentration-dependent regulation: low concentrations promoted growth, locomotion, feeding, and reproduction, while high concentrations induced developmental inhibition and reduced activity. This work provides a theoretical basis for the rational development of JHPCH resources.",
  "abstract_shown": true,
  "affiliations": [
    "School of Bioengineering, , Huainan 232038, China",
    "College of Life and Environmental Sciences, , Huangshan 245700, China",
    "School of Tourism, , Huangshan 245700, China"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Xueqing Geng"
    },
    {
      "affs": [
        0
      ],
      "name": "Xingchi Zhang"
    },
    {
      "affs": [
        0
      ],
      "name": "Yun Wang"
    },
    {
      "affs": [
        1
      ],
      "name": "Ting Yao"
    },
    {
      "affs": [
        2
      ],
      "name": "Zhuoting Gan"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/9fwrb1qn3kmh8.bib",
  "cited_by": 0,
  "doi": "10.3390/molecules31193542",
  "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13667172/?tool=EBI",
  "id": "9fwrb1qn3kmh8",
  "issns": [
    "1420-3049"
  ],
  "landing_url": "https://europepmc.org/article/PMC/PMC13667172",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1106|Polysaccharides Composition and Applications"
    ]
  ],
  "openalex": "W7220411566",
  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13667172/pdf/?tool=EBI",
  "pmcid": "PMC13667172",
  "pmid": null,
  "published": "2026-10-01",
  "publisher": "MDPI AG",
  "ris": "https://research.draconitic.com/paper/9fwrb1qn3kmh8.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:31Z",
      "native_id": "PMC:PMC13667172",
      "source": "europepmc",
      "url": "https://europepmc.org/article/PMC/PMC13667172"
    },
    {
      "first_seen": "2026-10-30T12:18:42Z",
      "native_id": "10.3390/molecules31193542",
      "source": "crossref",
      "url": "https://www.mdpi.com/1420-3049/31/19/3542"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "issn:1420-3049",
      "subfield": "general"
    }
  ],
  "title": "Polygonatum cyrtonema Hua in Jiuhua Mountain: Structural Characterization and Biological Activity",
  "title_text": "Polygonatum cyrtonema Hua in Jiuhua Mountain: Structural Characterization and Biological Activity",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:18:42Z",
  "url": "https://research.draconitic.com/paper/9fwrb1qn3kmh8",
  "venue": "Molecules (Basel, Switzerland)",
  "versions": []
}