{
  "abstract": "We report the first electrochemically hole-catalyzed (3+2) dearomative cycloaddition of nitroarenes, including benzene-based derivatives. Enabled by a hole-transfer chain process, the reaction proceeds through the anodic generation of a non-stabilized azomethine ylide from a readily available precursor, providing efficient access to structurally complex pyrrolidines from a broad range of electron-deficient nitroarenes. Remarkably, full conversion is achieved using catalytic amounts of electricity (0.1 F mol-1), resulting in high TONe (222) and Faradaic efficiency (925%). This work expands the scope of hole electrocatalysis beyond electron-rich olefins and establishes a new platform for electrochemical dearomative cycloadditions. The scalability of the method was further demonstrated under continuous-flow conditions.",
  "abstract_shown": true,
  "affiliations": [
    "ENSICAEN",
    "Institut CARMeN UMR",
    "UMR 7616 CNRS"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Nathan Noël"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Youssou Faye"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Julien Legros"
    },
    {
      "name": "Laëtitia Chausset-Boissarie",
      "orcid": "0000-0002-9549-057X"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Isabelle Chataigner"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/9g3m7ey39gg7q.bib",
  "cited_by": 0,
  "doi": "10.26434/chemrxiv.15009160/v1",
  "fulltext_url": null,
  "id": "9g3m7ey39gg7q",
  "issns": [],
  "landing_url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15009160/v1",
  "language": null,
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1605|Radical Photochemical Reactions"
    ]
  ],
  "openalex": "W7213891062",
  "pdf_url": "https://chemrxiv.org/doi/pdf/10.26434/chemrxiv.15009160/v1",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-21",
  "publisher": "American Chemical Society (ACS)",
  "ris": "https://research.draconitic.com/paper/9g3m7ey39gg7q.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:19Z",
      "native_id": "10.26434/chemrxiv.15009160",
      "source": "chemrxiv",
      "url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15009160/v1"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1605|Radical Photochemical Reactions",
      "subfield": "organic"
    }
  ],
  "title": "Electrochemically Hole-catalyzed Dearomative (3+2) Cycloaddition of Nitroarenes",
  "title_text": "Electrochemically Hole-catalyzed Dearomative (3+2) Cycloaddition of Nitroarenes",
  "type": "preprint",
  "updated_at": "2026-10-30T12:17:19Z",
  "url": "https://research.draconitic.com/paper/9g3m7ey39gg7q",
  "venue": "ChemRxiv",
  "versions": []
}