{
  "abstract": "Amiodarone is a class III anti-arrhythmic medication, which may result in possible ocular adverse effects. Amiodarone-associated retinopathy is infrequently perceived but is a potentially vision-threatening condition. We presented two rare cases of amiodarone-associated retinopathy. Their spectrum domain optical coherence tomography (SD-OCT) depicted loss of inner segment/outer segment (IS/OS) and cone outer segment tips (COSTs) lines at the macular region, sparing the external limiting membrane. One case exhibited additional hyperreflective spots at the subretinal layer on SD-OCT. Following the discontinuation of amiodarone and the administration of vitamin C eye drops, a partial recovery in the IS/OS and COST lines was observed.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "name": "Chun Pao Chang"
    },
    {
      "name": "Hung-Chi Chen"
    },
    {
      "name": "An-Ning Chao"
    },
    {
      "name": "Laura Liu"
    },
    {
      "name": "Kuan-Jen Chen"
    },
    {
      "name": "Yi-Hsing Chen"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/9g3pg1sekynzk.bib",
  "cited_by": 0,
  "doi": "10.4103/tjo.tjo-d-23-00151",
  "fulltext_url": "https://www.ovid.com/jnls/tjop/fulltext/10.4103/tjo.tjo-d-23-00151~clinical-observations-of-features-in-spectrum-domain-optical",
  "id": "9g3pg1sekynzk",
  "issns": [
    "2211-5056",
    "2211-5072"
  ],
  "landing_url": "https://doi.org/10.4103/tjo.tjo-d-23-00151",
  "language": "en",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "RE1-994"
    ],
    [
      "openalex",
      "2731|Drug-Induced Ocular Toxicity"
    ]
  ],
  "openalex": "W4410062708",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-07-01",
  "publisher": "Wolters Kluwer Medknow Publications",
  "ris": "https://research.draconitic.com/paper/9g3pg1sekynzk.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:43:53Z",
      "native_id": "487aabba29774f3095ad7baa610b56d8",
      "source": "doaj",
      "url": "https://doi.org/10.4103/tjo.tjo-d-23-00151"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2731|Drug-Induced Ocular Toxicity",
      "subfield": "general"
    }
  ],
  "title": "Clinical observations of features in spectrum domain optical coherence tomography of amiodarone-induced retinopathy: Two case presentation",
  "title_text": "Clinical observations of features in spectrum domain optical coherence tomography of amiodarone-induced retinopathy: Two case presentation",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:43:53Z",
  "url": "https://research.draconitic.com/paper/9g3pg1sekynzk",
  "venue": "Taiwan Journal of Ophthalmology",
  "versions": []
}