{
  "abstract": "Newcastle disease virus is one of the most highly contagious infections impacting poultry industries worldwide. This study aimed to develop a bacteriophage display system as a cost-effective and immunogenic method for expressing the immunodominant region of the Newcastle Disease Virus Fusion (F) protein for use in serological assays. Both in-silico and in-vitro analyses indicated that the selected antigen is stable, accurate, and reliable for further in-vivo studies. The displayed antigen successfully detected NDV-GVII-specific antibodies in vaccinated chickens. Additionally, a significant correlation was observed between ELISA and HI test results on chicken serum samples. This approach addresses safety concerns associated with wild-type virulent NDVs and offers improved diagnostic accuracy and scalability, aligning with industry needs for improved Newcastle disease detection, control, and management on poultry farms.",
  "abstract_shown": true,
  "affiliations": [
    "School of Animal and Veterinary Sciences, Adelaide University",
    "Institute for Applied Ecology, University of Canberra",
    "State Key Laboratory of Genetics and Development of Complex Phenotypes, School of Life Sciences, Fudan University",
    "Research Organization for Health, National Research and Innovation Agency (BRIN)",
    "Research Center for Veterinary Science, Research Organization for Health, National Research and Innovation Agency (BRIN)",
    "Department of Pathobiology, School of Veterinary Medicine, Shiraz University",
    "UniSA Clinical & Health Sciences, University of South Australia",
    "Universitas Nusa Cendana, Fakultas Kedokteran dan Kedokteran Hewan(FKKH)"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 21,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Mehrnaz Najafi"
    },
    {
      "affs": [
        0
      ],
      "name": "Hanh Thi Hong Nguyen"
    },
    {
      "affs": [
        0
      ],
      "name": "Bahareh Pakbaten"
    },
    {
      "affs": [
        1
      ],
      "name": "Aliakbar Khabiri"
    },
    {
      "affs": [
        0
      ],
      "name": "Abdollah Derakhshandeh"
    },
    {
      "affs": [
        2
      ],
      "name": "Chen Ling"
    },
    {
      "affs": [
        3
      ],
      "name": "Ni Luh Puti Indi Dharmayanti"
    },
    {
      "affs": [
        4
      ],
      "name": "Harimurti Nuradji"
    },
    {
      "affs": [
        4
      ],
      "name": "Faidah Rahmawati"
    },
    {
      "affs": [
        4
      ],
      "name": "Rahmat Setya Adji"
    },
    {
      "affs": [
        4
      ],
      "name": "Nuha Fairunisya"
    },
    {
      "affs": [
        4
      ],
      "name": "Fitirine Ekawasti"
    },
    {
      "affs": [
        4
      ],
      "name": "Prima Mei Widiy"
    },
    {
      "affs": [
        4
      ],
      "name": "Tati Ariyanti"
    },
    {
      "affs": [
        0
      ],
      "name": "Ngoc X. B. Nguyen"
    },
    {
      "affs": [
        0
      ],
      "name": "Kandarp Patel"
    },
    {
      "affs": [
        5
      ],
      "name": "Maryam Sadat Moezzi"
    },
    {
      "affs": [
        0
      ],
      "name": "Mohammad Indro Cahyono"
    },
    {
      "affs": [
        6
      ],
      "name": "Sammi Yuen Tung Ngai"
    },
    {
      "affs": [
        7
      ],
      "name": "Putri Pandarangga"
    },
    {
      "affs": [
        0
      ],
      "name": "Farhid Hemmatzadeh"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/9gsjmb6k9t35g.bib",
  "cited_by": 0,
  "doi": "10.1038/s41598-026-60560-4",
  "fulltext_url": "https://doi.org/10.1038/s41598-026-60560-4",
  "id": "9gsjmb6k9t35g",
  "issns": [
    "2045-2322"
  ],
  "landing_url": "https://doi.org/10.1038/s41598-026-60560-4",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "Q"
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      "lcc",
      "R"
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      "openalex",
      "2713|Virology and Viral Diseases"
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  "openalex": "W7169777171",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-07-01",
  "publisher": "Nature Portfolio",
  "ris": "https://research.draconitic.com/paper/9gsjmb6k9t35g.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:45:57Z",
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      "url": "https://doi.org/10.1038/s41598-026-60560-4"
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  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2713|Virology and Viral Diseases",
      "subfield": "epidemiology-public-health"
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  ],
  "title": "Development of a novel phage-displayed fusion protein of newcastle disease virus as a highly specific antigen for serological assays",
  "title_text": "Development of a novel phage-displayed fusion protein of newcastle disease virus as a highly specific antigen for serological assays",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:45:57Z",
  "url": "https://research.draconitic.com/paper/9gsjmb6k9t35g",
  "venue": "Scientific Reports",
  "versions": []
}