{
  "abstract": "Background: Clinical pregnancy rate is the outcome most commonly reported in trials of platelet-rich plasma (PRP) as an adjunct for recurrent implantation failure (RIF) [6-11], yet live birth — the outcome of greatest relevance to patients — is rarely assessed. Objective: To determine live birth rate, miscarriage rate, and pregnancy continuation among women who achieved clinical pregnancy after sub-endometrial PRP injection (SE-PRP), intrauterine PRP infusion (IU-PRP), or standard hormonal preparation alone (control), as a follow-up of a previously completed three-arm randomized controlled trial [1]. Methods: This follow-up cohort study traced pregnancy outcome for all 59 women who achieved clinical pregnancy in the parent trial [1] (SE-PRP = 24, IU-PRP = 20, control = 15) through to delivery or pregnancy loss. Results: Live birth occurred in 15/60 (25.0%) in the SE-PRP group, 12/60 (20.0%) in the IU-PRP group, and 8/60 (13.3%) in the control group (χ² = 2.62, p = 0.27). Among women who achieved clinical pregnancy, live birth rate was 62.5%, 60.0%, and 53.3% respectively (p = 0.85), with no significant between-group difference in pregnancy continuation once implantation had occurred. Conclusion: Live birth rate followed the same numerical hierarchy (SE-PRP > IU-PRP > control) observed for clinical pregnancy in the parent trial [1], though the difference did not reach statistical significance. The similarity in pregnancy-continuation rate across groups suggests that the principal contribution of PRP — and of its delivery route — operates at the level of implantation rather than throughout gestation.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Obstetrics and Gynecology, Faculty of Medicine ,Minia University",
    "Department of Obstetrics and Gynecology, faculty of medicine, Minia University",
    "department of Obstetrics and Gynecology, faculty of medicine minia University"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Mohammed Saber"
    },
    {
      "affs": [
        1
      ],
      "name": "Abdelbaset Abdelbaset"
    },
    {
      "affs": [
        1
      ],
      "name": "Ahmed Abdelmalik"
    },
    {
      "affs": [
        2
      ],
      "name": "Enas Mohammed"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/9hz41vkzpy0ca.bib",
  "cited_by": 0,
  "doi": "10.21608/mjmr.2026.537183.2407",
  "fulltext_url": "https://mjmr.journals.ekb.eg/article_535258.html",
  "id": "9hz41vkzpy0ca",
  "issns": [
    "2682-4558"
  ],
  "landing_url": "https://doi.org/10.21608/mjmr.2026.537183.2407",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "R"
    ],
    [
      "openalex",
      "2403|Reproductive System and Pregnancy"
    ]
  ],
  "openalex": "W7225052714",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-01",
  "publisher": "Minia University, Faculty of Medicine",
  "ris": "https://research.draconitic.com/paper/9hz41vkzpy0ca.ris",
  "sources": [
    {
      "first_seen": "2026-11-08T14:20:48Z",
      "native_id": "0ddd7dc1d12e412d8b764bc31e100304",
      "source": "doaj",
      "url": "https://doi.org/10.21608/mjmr.2026.537183.2407"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:2403|Reproductive System and Pregnancy",
      "subfield": "immunology"
    }
  ],
  "title": "​Live Birth Outcomes Following subendometrial platelet rich plasma versus Intrauterine platelet rich plasma infusion in Women with Recurrent Implantation Failure: A Cohort Study",
  "title_text": "​Live Birth Outcomes Following subendometrial platelet rich plasma versus Intrauterine platelet rich plasma infusion in Women with Recurrent Implantation Failure: A Cohort Study",
  "type": "peer-reviewed",
  "updated_at": "2026-11-08T14:20:48Z",
  "url": "https://research.draconitic.com/paper/9hz41vkzpy0ca",
  "venue": "Minia Journal of Medical Research",
  "versions": []
}