{
  "abstract": "An 81-year-old Japanese man with IgG4-related disease (IgG4-RD) presented with marked edema in the right lower leg. He was diagnosed with IgG4-RD with retroperitoneal fibrosis, hilar and mediastinal lymphadenopathy, elevated serum IgG4 levels, and IgG4-positive plasma cell infiltration in a mediastinal lymph node. Lymphatic scintigraphy revealed an obstruction corresponding to edema due to retroperitoneal fibrosis. Glucocorticoid therapy resulted in rapid improvement. Lymphedema due to IgG4-RD with retroperitoneal fibrosis is rare and no standard treatment exists. This case underscores the importance of considering IgG4-RD which is a potentially reversible cause of lymphedema.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 9,
  "authors": [
    {
      "name": "Yuta Matsushita"
    },
    {
      "name": "Masataka Umeda"
    },
    {
      "name": "Hirokazu Kurohama"
    },
    {
      "name": "Tomoki Origuchi"
    },
    {
      "name": "Kanako Kojima"
    },
    {
      "name": "Yoshika Tsuji"
    },
    {
      "name": "Remi Sumiyoshi"
    },
    {
      "name": "Naoki Iwamoto"
    },
    {
      "name": "Atsushi Kawakami"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/9jddj799fyvsg.bib",
  "cited_by": 0,
  "doi": "10.2169/internalmedicine.6044-25",
  "fulltext_url": "https://www.jstage.jst.go.jp/article/internalmedicine/65/15/65_6044-25/_article",
  "id": "9jddj799fyvsg",
  "issns": [
    "1349-7235",
    "0918-2918"
  ],
  "landing_url": "https://www.jstage.jst.go.jp/article/internalmedicine/65/15/65_6044-25/_article",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "jstage-journal",
      "medicine/general"
    ],
    [
      "openalex",
      "2745|IgG4-Related and Inflammatory Diseases"
    ]
  ],
  "openalex": "W7117272968",
  "pdf_url": "https://www.jstage.jst.go.jp/article/internalmedicine/65/15/65_6044-25/_pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-08-01",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/9jddj799fyvsg.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:31Z",
      "native_id": "10.2169/internalmedicine.6044-25",
      "source": "jstage",
      "url": "https://www.jstage.jst.go.jp/article/internalmedicine/65/15/65_6044-25/_article"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2745|IgG4-Related and Inflammatory Diseases",
      "subfield": "general"
    }
  ],
  "title": "Improvement of Lymphedema in IgG4-Related Disease with Oral Glucocorticoid Therapy",
  "title_text": "Improvement of Lymphedema in IgG4-Related Disease with Oral Glucocorticoid Therapy",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:31Z",
  "url": "https://research.draconitic.com/paper/9jddj799fyvsg",
  "venue": "Internal Medicine",
  "versions": []
}