{
  "abstract": "Background/Objectives: Elastic-band resistance and plyometric training, which differ in eccentric and impact loading, are commonly added to tennis conditioning, but their effects on circulating markers related to extracellular-matrix turnover and antioxidant status are unknown. Methods: In this exploratory, matched, non-randomised controlled study, 24 collegiate tennis players (11 women, 13 men) were allocated to habitual tennis training only (CON) or to 8 weeks of additional elastic-band resistance (RBT) or plyometric training (PLY); 23 (CON 8, RBT 7, PLY 8) were analysed. Fasting serum MMP-2, MMP-9, TIMP-1, TIMP-2 and coenzyme Q10 (CoQ10) were measured by enzyme-linked immunosorbent assay (ELISA) approximately 24 h after the final session and compared by baseline-adjusted analysis of covariance with multiplicity control and sensitivity analyses. Results: Baseline-adjusted CoQ10 was lower in RBT than in CON (Hedges’ g −0.86, 95% CI −1.47 to −0.26) and PLY (g −0.80, 95% CI −1.48 to −0.12); in RBT, CoQ10 fell from 16.6 ± 4.3 to 8.3 ± 1.9 ng/mL. Adjusted TIMP-1 was lower in both training groups than in CON, reflecting an increase in CON rather than a decrease with training. TIMP-2 was lower in RBT than in CON and PLY (g −1.00 and −1.10), but this was not confirmed by rank-based analysis. MMP-9 fell over time in all groups without a group effect, and MMP-2 was unchanged. Conclusions: In this small, non-randomised study, adding elastic-band training to tennis practice was associated with lower serum CoQ10 and, less robustly, TIMP-2; plyometric training was not associated with changes beyond those seen in all groups, although only very large effects were detectable. These hypothesis-generating findings require confirmation in adequately powered randomised trials using chromatographic CoQ10 measurement.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Physical Education and Sports, Faculty of Sport Sciences, Van Yuzuncu Yil University, 65090 Van, Türkiye",
    "Bafra Vocational School, Ondokuz Mayıs University, 55400 Samsun, Türkiye",
    "Department of Biochemistry, Faculty of Medicine, Van Yuzuncu Yil University, 65090 Van, Türkiye",
    "Department of Physical Education and Sports, Faculty of Sport Sciences, Fırat University, 23119 Elazığ, Türkiye",
    "Department of Coaching Education, Faculty of Sport Sciences, Van Yuzuncu Yil University, 65090 Van, Türkiye"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Emine Büyükkaya"
    },
    {
      "affs": [
        0
      ],
      "name": "Salih Öner",
      "orcid": "0000-0002-6643-7665"
    },
    {
      "affs": [
        1
      ],
      "name": "Yavuz Yasul",
      "orcid": "0000-0002-9458-1664"
    },
    {
      "affs": [
        2
      ],
      "name": "Hamit Hakan Alp"
    },
    {
      "affs": [
        3
      ],
      "name": "Vedat Çınar"
    },
    {
      "affs": [
        4
      ],
      "name": "Beyza Ertan",
      "orcid": "0000-0001-7202-5555"
    },
    {
      "affs": [
        3
      ],
      "name": "Mustafa Karadağ"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/9k4sjsn2sqmkh.bib",
  "cited_by": 0,
  "doi": "10.3390/metabo16100801",
  "fulltext_url": "https://europepmc.org/articles/PMC13707224",
  "id": "9k4sjsn2sqmkh",
  "issns": [
    "2218-1989"
  ],
  "landing_url": "https://www.mdpi.com/2218-1989/16/10/801",
  "language": "eng",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2732|Sports Performance and Training"
    ]
  ],
  "openalex": "W7223182143",
  "pdf_url": "https://europepmc.org/articles/PMC13707224?pdf=render",
  "pmcid": "PMC13707224",
  "pmid": "42941276",
  "published": "2026-10-21",
  "publisher": "MDPI AG",
  "ris": "https://research.draconitic.com/paper/9k4sjsn2sqmkh.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:00Z",
      "native_id": "10.3390/metabo16100801",
      "source": "crossref",
      "url": "https://www.mdpi.com/2218-1989/16/10/801"
    },
    {
      "first_seen": "2026-10-30T12:22:12Z",
      "native_id": "MED:42941276",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42941276"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2732|Sports Performance and Training",
      "subfield": "surgery"
    }
  ],
  "title": "Effects of Elastic-Band Resistance and Plyometric Training on Serum MMP-2, MMP-9, TIMPs and Coenzyme Q10 in Collegiate Tennis Players: An Exploratory, Non-Randomised Three-Arm Controlled Study",
  "title_text": "Effects of Elastic-Band Resistance and Plyometric Training on Serum MMP-2, MMP-9, TIMPs and Coenzyme Q10 in Collegiate Tennis Players: An Exploratory, Non-Randomised Three-Arm Controlled Study",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:22:12Z",
  "url": "https://research.draconitic.com/paper/9k4sjsn2sqmkh",
  "venue": "Metabolites",
  "versions": []
}