{
  "abstract": "Objective: To identify latent profiles of postoperative day-7 cognitive performance among older adults after elective surgery and to explore demographic, behavioral, clinical, and social factors associated with profile membership.\n\nMethods: This prospective observational study included 308 consecutively recruited patients aged ≥65 years who underwent elective surgery under general anesthesia. Cognition was assessed with the Mini-Mental State Examination (MMSE), and latent profile analysis used five study-defined postoperative domain scores. Candidate correlates were organized with the health ecological model and examined using univariate tests and posterior-probability-weighted exploratory multinomial regression.\n\nResults: Three severity-ordered profiles were identified: low (n=83, 26.9%), intermediate (n=72, 23.4%), and high postoperative cognitive performance (n=153, 49.7%). Older age and lower education were associated with both lower-performance profiles. Greater activities-of-daily-living dependence, lower income, and living alone were associated with the low-performance profile, whereas poorer sleep was associated with the intermediate-performance profile.\n\nConclusions: Day-7 MMSE performance formed a severity gradient across three data-driven profiles. These cross-sectional profiles do not demonstrate postoperative decline, a clinical diagnosis, or an effect attributable specifically to general anesthesia. Longitudinal studies with retained baseline scores, appropriate comparison groups, and broader neuropsychological assessment are required before profile-specific interventions can be recommended.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Cardiothoracic and Vascular Surgery, Jingzhou Central Hospital",
    "Medical School, Yangtze University",
    "Department of Neurology, Jingzhou Central Hospital"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Yao Liao"
    },
    {
      "affs": [
        1
      ],
      "name": "Xuanying Zhang"
    },
    {
      "affs": [
        2
      ],
      "name": "Yunlei Zhang"
    },
    {
      "affs": [
        1
      ],
      "name": "Lunmei Shi"
    },
    {
      "affs": [
        2
      ],
      "name": "Yalin Liu"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/9kecy9vf9acq8.bib",
  "cited_by": 0,
  "doi": "10.3389/fpsyt.2026.1975739",
  "fulltext_url": null,
  "id": "9kecy9vf9acq8",
  "issns": [
    "1664-0640"
  ],
  "landing_url": "https://www.frontiersin.org/articles/10.3389/fpsyt.2026.1975739/full",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2706|Intensive Care Unit Cognitive Disorders"
    ]
  ],
  "openalex": "W7224135610",
  "pdf_url": "https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2026.1975739/pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-28",
  "publisher": "Frontiers Media SA",
  "ris": "https://research.draconitic.com/paper/9kecy9vf9acq8.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:20:18Z",
      "native_id": "10.3389/fpsyt.2026.1975739",
      "source": "crossref",
      "url": "https://www.frontiersin.org/articles/10.3389/fpsyt.2026.1975739/full"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "issn:1664-0640",
      "subfield": "psychiatry"
    }
  ],
  "title": "Latent profiles of day-7 cognitive performance and associated ecological factors in older adults after elective surgery: an observational study",
  "title_text": "Latent profiles of day-7 cognitive performance and associated ecological factors in older adults after elective surgery: an observational study",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:20:18Z",
  "url": "https://research.draconitic.com/paper/9kecy9vf9acq8",
  "venue": "Frontiers in Psychiatry",
  "versions": []
}