{
  "abstract": "Plasmonic nanopores have been used to trap single nanoparticles using electric bias for single-molecule surface enhanced Raman spectroscopic (SM-SERS) detection and sequencing. While they exhibit high sensitivity, removal of nanoparticle clusters in the nanopore is so labor intensive that it hampers biosensing applications. Here, our approach is to use a microcontroller to change the electric voltage to remove the nanoparticle clusters in the nanopore with feedback by the Raman spectra. The SM-SERS spectra of the molecules adsorbed on nanoparticle surface can be acquired over a sufficiently long period, so that the microcontroller can analyze them with <100 ms and trigger the voltage change to remove the nanoparticle cluster. Our system is promising for automatic and high-throughput SM-SERS detection and analysis of DNA and proteins.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": "2609.15469",
  "author_total": 8,
  "authors": [
    {
      "name": "Iuliia Sheinman"
    },
    {
      "name": "Yingqi Zhao"
    },
    {
      "name": "Zhendai Huang"
    },
    {
      "name": "Kuo Zhan"
    },
    {
      "name": "Zuyan Chen"
    },
    {
      "name": "Ilkka Nissinen"
    },
    {
      "name": "Shuai Li"
    },
    {
      "name": "Jianan Huang"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/9nbgt4x1psjgw.bib",
  "cited_by": 0,
  "doi": "10.48550/arxiv.2609.15469",
  "fulltext_url": null,
  "id": "9nbgt4x1psjgw",
  "issns": [],
  "landing_url": "https://arxiv.org/abs/2609.15469",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "http://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": "CC0-1.0",
  "native_subjects": [
    [
      "arxiv",
      "physics.optics"
    ],
    [
      "openalex",
      "2504|Gold and Silver Nanoparticles Synthesis and Applications"
    ]
  ],
  "openalex": "W7213365417",
  "pdf_url": "https://arxiv.org/pdf/2609.15469",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-14",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/9nbgt4x1psjgw.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:21:25Z",
      "native_id": "2609.15469",
      "source": "arxiv",
      "url": "https://arxiv.org/abs/2609.15469"
    }
  ],
  "subjects": [
    {
      "field": "physics",
      "origin": "arxiv:physics.optics",
      "subfield": "optics-photonics"
    }
  ],
  "title": "Automatic control of gold nanoparticle clustering in plasmonic nanopores based on Raman spectroscopic feedback",
  "title_text": "Automatic control of gold nanoparticle clustering in plasmonic nanopores based on Raman spectroscopic feedback",
  "type": "preprint",
  "updated_at": "2026-10-30T12:21:25Z",
  "url": "https://research.draconitic.com/paper/9nbgt4x1psjgw",
  "venue": "arXiv",
  "versions": []
}