{
  "abstract": "Purpose of the Review: This review examines the progress made in neuromodulation therapies for UUI since the original introduction of SNM devices until now. There are multiple current commercial neuromodulation therapies from which to choose, including those with sacral or tibial nerve targets. The intent is to provide critical evidence to help clinicians decide which device to offer their patients.\n\nRecent Findings: Modern SNM systems consistently outperform both previous-generation SNM and contemporary iTNM. Modern SNM demonstrates substantially higher effectiveness than pooled averages including early device studies with outdated study designs, tools and implant techniques. Current iTNM outcomes are comparable to legacy SNM yet remain markedly lower than modern SNM.\n\nSummary: Contemporary data supports a clear hierarchy—modern SNM offers the highest effectiveness and the most favorable safety profile. We believe that our field is moving toward minimally invasive, highly targeted, patient-directed SNM systems—an evolution that aligns with both clinical outcomes and patient preferences.\n\nSupplementary Information: The online version contains supplementary material available at https://doi.org/10.1007/s11934-026-01377-6.",
  "abstract_shown": true,
  "affiliations": [
    "Neuspera Medical, Inc, 51 Dagget Dr, CA San Jose, 95134 USA",
    "Minnesota Urology, Woodbury, MN USA",
    "Department of Urology, Indiana University School of Medicine, Indianapolis, IN USA",
    "Department of Urology, Vanderbilt University Medical Center, Nashville, TN USA"
  ],
  "article_type": "review article",
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Steven Siegel"
    },
    {
      "affs": [
        1
      ],
      "name": "Michael J Ehlert"
    },
    {
      "affs": [
        2
      ],
      "name": "Charles R. Powell"
    },
    {
      "affs": [
        3
      ],
      "name": "Melissa Kaufman"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/9ncwt5nc7hgde.bib",
  "cited_by": 0,
  "doi": "10.1007/s11934-026-01377-6",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13736484/",
  "id": "9ncwt5nc7hgde",
  "issns": [
    "1527-2737",
    "1534-6285"
  ],
  "landing_url": "https://doi.org/10.1007/s11934-026-01377-6",
  "language": "en",
  "licence": "CC-BY-NC-ND-4.0",
  "licence_label": "CC BY-NC-ND 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Review"
    ],
    [
      "openalex",
      "2748|Urinary Bladder and Prostate Research"
    ]
  ],
  "openalex": "W7225236505",
  "pdf_url": "https://link.springer.com/content/pdf/10.1007/s11934-026-01377-6.pdf",
  "pmcid": "PMC13736484",
  "pmid": "42982928",
  "published": "2026-11-04",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/9ncwt5nc7hgde.ris",
  "sources": [
    {
      "first_seen": "2026-11-09T12:21:55Z",
      "native_id": "PMC13736484",
      "source": "pmc",
      "url": "https://doi.org/10.1007/s11934-026-01377-6"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2748|Urinary Bladder and Prostate Research",
      "subfield": "general"
    }
  ],
  "title": "Past, Present, and Future Implantable Neuromodulation Treatments for Management of Urinary Urge Incontinence (UUI): Implications for Clinical Effectiveness and Safety",
  "title_text": "Past, Present, and Future Implantable Neuromodulation Treatments for Management of Urinary Urge Incontinence (UUI): Implications for Clinical Effectiveness and Safety",
  "type": "peer-reviewed",
  "updated_at": "2026-11-09T12:21:55Z",
  "url": "https://research.draconitic.com/paper/9ncwt5nc7hgde",
  "venue": "Current Urology Reports",
  "versions": []
}