{
  "abstract": "BACKGROUND: The recently published Rome V adult diagnostic criteria facilitated an updated epidemiological survey of disorders of gut-brain interaction (DGBI). OBJECTIVE: We aimed to describe the global epidemiology of DGBI using the Rome V criteria and compare it with the Rome IV Rome Foundation Global Epidemiology Study. METHODS: A population-based Internet survey of 28,771 adults was conducted in 15 countries using the Rome V diagnostic questionnaire. DGBI prevalence was determined and compared with the Rome IV data. Multivariable logistic regression models were used to examine associations of demographic factors to Rome V DGBI status in the global population and to assess potentially associated clinical factors. RESULTS: The surveys yielded similar results. The prevalence of at least one DGBI using the Rome V criteria was 40.9%, compared with 40.5% for Rome IV. In both, the prevalence was higher among females and decreased with increasing age. In the Rome V sample (25 DGBI), the most prevalent oesophageal disorder was functional dysphagia at 4.1%, the most prevalent gastroduodenal disorder was functional dyspepsia at 8.1%, unclassified bowel disorder was the most prevalent bowel disorder (9.6%), followed by chronic constipation (8.9%) and IBS (8.5%) and proctalgia fugax was the most prevalent anorectal disorder (7.3%). The prevalence rates for two new DGBI were 5.1% for abdominal migraine and 1.4% for inability to belch syndrome. CONCLUSION: The Rome V global prevalence of DGBI is consistent with Rome IV. This bolsters confidence in the validity of prevalence rates for DGBI and reaffirms their high global burden.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 23,
  "authors": [
    {
      "name": "Ami Sperber"
    },
    {
      "name": "Johann Hreinsson"
    },
    {
      "name": "Magnus Simrén"
    },
    {
      "name": "Douglas Drossman"
    },
    {
      "name": "Viola Andresen"
    },
    {
      "name": "Serhat Bor"
    },
    {
      "name": "Dan Dumitrascu"
    },
    {
      "name": "Xiucai Fang"
    },
    {
      "name": "Guijun Fei"
    },
    {
      "name": "Luis Bustos Fernandez"
    },
    {
      "name": "Carlos Francesconi"
    },
    {
      "name": "Shin Fukudo"
    },
    {
      "name": "Sang Kil Lee"
    },
    {
      "name": "Chloé Melchior"
    },
    {
      "name": "Agata Mulak"
    },
    {
      "name": "Anne Peery"
    },
    {
      "name": "David Rodrigues"
    },
    {
      "name": "Javier Santos"
    },
    {
      "name": "Max Schmulson"
    },
    {
      "name": "Dipesh Vasant"
    },
    {
      "name": "Jan Tack"
    },
    {
      "name": "Tiffany Taft"
    },
    {
      "name": "Olafur Palsson"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/9p1vh4v7nyngn.bib",
  "cited_by": 5,
  "doi": "10.1136/gutjnl-2026-339666",
  "fulltext_url": null,
  "id": "9p1vh4v7nyngn",
  "issns": [
    "0017-5749",
    "1468-3288"
  ],
  "landing_url": "https://normandie-univ.hal.science/hal-05771332v1",
  "language": "en",
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.sdv"
    ],
    [
      "openalex",
      "2715|Gastrointestinal motility and disorders"
    ]
  ],
  "openalex": "W7203686505",
  "pdf_url": "https://gut.bmj.com/content/gutjnl/early/2026/08/16/gutjnl-2026-339666.full.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-08-18",
  "publisher": "BMJ Publishing Group",
  "ris": "https://research.draconitic.com/paper/9p1vh4v7nyngn.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:44Z",
      "native_id": "hal-05771332",
      "source": "hal",
      "url": "https://normandie-univ.hal.science/hal-05771332v1"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "hal:0.sdv",
      "subfield": "general"
    }
  ],
  "title": "Rome V global epidemiology and validation survey: prevalence of disorders of gut–brain interaction and comparison with the Rome IV global epidemiology study",
  "title_text": "Rome V global epidemiology and validation survey: prevalence of disorders of gut–brain interaction and comparison with the Rome IV global epidemiology study",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:44Z",
  "url": "https://research.draconitic.com/paper/9p1vh4v7nyngn",
  "venue": "Gut",
  "versions": []
}