{
  "abstract": "“Immuniser Lyon” (IL) is a French city-level initiative launched in 2015 to promote vaccination through coordinated, locally tailored actions. The objective of this study is to describe and compare temporal trends in vaccine coverage for HPV and influenza in the Rhône area versus the neighboring Auvergne-Rhône-Alpes (ARA) region, and to explore whether observed patterns are consistent with a potential contribution of the IL initiative. A comparative analysis of vaccine coverage was performed for HPV (2010–2022) and influenza (2016–2020) between different areas within the Auvergne-Rhône-Alpes (ARA) region versus the ARA region, using binomial log-linear models. HPV vaccine coverage in Rhône and ARA followed similar patterns, increasing from 2015 to 2022 after a nationwide decline. For influenza, vaccine coverage among adults aged ≥65 was significantly higher in Lyon in 2020 (64.5%) than in the rest of ARA (59.2%, OR=1.25, 95% CI [1.24–1.26], p < 0.001). While HPV trends reflected broader national dynamics, the observed pattern may be consistent with a potential contribution of IL to the accelerated uptake of influenza vaccines in older adults. These findings highlight the potential of sustained local action to complement national immunization strategies.",
  "abstract_shown": true,
  "affiliations": [
    "PHE3ID, International Center for Research in Infectiology, Inserm U1111, CNRS UMR5308, ENS de Lyon, University Lyon 1, Lyon, France",
    "Claude Bernard University, Lyon 1 University, Lyon, France",
    "Service Hygiène, Epidémiologie, Infectiovigilance et Prévention, Hospices Civils de Lyon, Lyon, France",
    "Regional health monitoring center, Auvergne-Rhône-Alpes Regional Health Agency, Lyon, France",
    "Academy of Pharmacy, Lyon, France",
    "Doctor, Former Director of Urban Ecology, Lyon, France",
    "Blossom Vaccinology, La Chapelle du Mont du Chat, France",
    "Laboratoire de Biométrie et Biologie Evolutive, CNRS UMR5558, Equipe Biostatistiques Santé, Villeurbanne, France",
    "Service de Biostatistique-Bioinformatique, Hospices Civils de Lyon, Lyon, France"
  ],
  "article_type": "Research Article",
  "arxiv": null,
  "author_total": 9,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Juliette Dessemon"
    },
    {
      "affs": [
        1
      ],
      "name": "Romain Saux"
    },
    {
      "affs": [
        2
      ],
      "name": "Christelle Elias"
    },
    {
      "affs": [
        3
      ],
      "name": "Anne-Sophie Ronnaux-Baron"
    },
    {
      "affs": [
        4
      ],
      "name": "Anne Sophie Malachane"
    },
    {
      "affs": [
        5
      ],
      "name": "Sophie Pamies-Jeantet"
    },
    {
      "affs": [
        6
      ],
      "name": "Benoit Soubeyrand"
    },
    {
      "affs": [
        7
      ],
      "name": "Pascal Roy"
    },
    {
      "affs": [
        8
      ],
      "name": "Philippe Vanhems"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/9q6xpdnht9zja.bib",
  "cited_by": 0,
  "doi": "10.1371/journal.pgph.0007468",
  "fulltext_url": "https://journals.plos.org/globalpublichealth/article?id=10.1371/journal.pgph.0007468",
  "id": "9q6xpdnht9zja",
  "issns": [
    "2767-3375"
  ],
  "landing_url": "https://journals.plos.org/globalpublichealth/article?id=10.1371/journal.pgph.0007468",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "3306|Vaccine Coverage and Hesitancy"
    ],
    [
      "plos",
      "/Biology and life sciences/Immunology/Vaccination and immunization"
    ],
    [
      "plos",
      "/Biology and life sciences/Microbiology/Medical microbiology/Microbial pathogens/Viral pathogens/Papillomaviruses/Human papillomavirus"
    ],
    [
      "plos",
      "/Biology and life sciences/Organisms/Viruses/DNA viruses/Papillomaviruses/Human papillomavirus"
    ],
    [
      "plos",
      "/Biology and life sciences/Organisms/Viruses/Viral pathogens/Papillomaviruses/Human papillomavirus"
    ],
    [
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      "/Earth sciences/Geography/Geographic areas/Urban areas"
    ],
    [
      "plos",
      "/Earth sciences/Geography/Human geography/Urban geography/Urban areas"
    ],
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      "/Medicine and health sciences/Epidemiology/Pandemics"
    ],
    [
      "plos",
      "/Medicine and health sciences/Immunology/Vaccination and immunization"
    ],
    [
      "plos",
      "/Medicine and health sciences/Medical conditions/Infectious diseases/Infectious disease control/Vaccines"
    ],
    [
      "plos",
      "/Medicine and health sciences/Medical conditions/Infectious diseases/Viral diseases/Influenza"
    ],
    [
      "plos",
      "/Medicine and health sciences/Pathology and laboratory medicine/Pathogens/Microbial pathogens/Viral pathogens/Papillomaviruses/Human papillomavirus"
    ],
    [
      "plos",
      "/Medicine and health sciences/Public and occupational health/Preventive medicine/Vaccination and immunization"
    ],
    [
      "plos",
      "/People and places/Geographical locations/Europe/European Union/France"
    ],
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      "plos",
      "/People and places/Population groupings/Age groups/Adults/Elderly"
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      "/Social sciences/Human geography/Urban geography/Urban areas"
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  "openalex": "W7222475158",
  "pdf_url": "https://journals.plos.org/globalpublichealth/article/file?id=10.1371/journal.pgph.0007468&type=printable",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-16",
  "publisher": "Public Library of Science",
  "ris": "https://research.draconitic.com/paper/9q6xpdnht9zja.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:23Z",
      "native_id": "10.1371/journal.pgph.0007468",
      "source": "plos",
      "url": "https://journals.plos.org/globalpublichealth/article?id=10.1371/journal.pgph.0007468"
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  "subjects": [
    {
      "field": "biology",
      "origin": "plos:immunology",
      "subfield": "immunology"
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    {
      "field": "medicine",
      "origin": "plos:epidemiology",
      "subfield": "epidemiology-public-health"
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    {
      "field": "medicine",
      "origin": "plos:infectious diseases",
      "subfield": "infectious-disease"
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  ],
  "title": "Assessing a local vaccination initiative: Eight years of “Immuniser Lyon” in France",
  "title_text": "Assessing a local vaccination initiative: Eight years of “Immuniser Lyon” in France",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:23Z",
  "url": "https://research.draconitic.com/paper/9q6xpdnht9zja",
  "venue": "PLOS Global Public Health",
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}