{
  "abstract": "BACKGROUND: Postoperative thrombocytopenia is a frequent complication in cardiac surgery, associated with increased morbidity and mortality. Our study aimed to describe platelet count after cardiac surgery and identify predictors of postoperative thrombocytopenia. METHODS: We conducted a retrospective, single-center study including 519 adult patients who underwent cardiac surgery without operative platelet transfusion. The primary outcome was the incidence of postoperative thrombocytopenia, defined using three thresholds: <150 G/L, <100 G/L, and <50 G/L. Platelet counts were recorded daily from preoperative day to postoperative day 7. Independent predictors were identified using multivariate logistic regression for a threshold of 100 G/L. RESULTS: Thrombocytopenia < 150 G/L occurred in 306 patients (59%), <100 G/L in 92 (18%), and < 50 G/L in 35 (7%). The incidence of thrombocytopenia depended on the type of surgery ( P < 0.0001). Mitral valve surgery, ascending aorta procedures, and the use of sutureless aortic valve prostheses were associated with increased thrombocytopenia rates. Platelet counts were higher in patients who have had off-pump coronary surgery within the first five days ( P < 0.0001). Five independent predictors were identified: older age ( P = 0.022), lower baseline platelet count ( P < 0.0001), higher creatinine ( P = 0.04), operative transfused units of red blood cells ( P = 0.015), and higher autotransfusion volume ( P = 0.02). The model using only preoperative variables achieved an AUC of 0.83. Finally, thrombocytopenia <100 G/L was associated with more blood loss ( P = 0.001), more postoperative transfusions ( P < 0.0001), and longer intensive care unit stay ( P = 0.001). CONCLUSION: Our study differentiates pre- and perioperative risk factors for thrombocytopenia in cardiac surgery to define a targeted, individualized platelet management strategy.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 9,
  "authors": [
    {
      "name": "David Haszon"
    },
    {
      "name": "Sahar Abdallah"
    },
    {
      "name": "Qingyan Jia"
    },
    {
      "name": "Thibaut Lutz"
    },
    {
      "name": "Stéphane Santiago"
    },
    {
      "name": "Marius Tifrea"
    },
    {
      "name": "Lucie Chastaingt"
    },
    {
      "name": "Jérome Jouan"
    },
    {
      "name": "David Vandroux"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/9qcmpmm60wraa.bib",
  "cited_by": 0,
  "doi": "10.4103/aca.aca_367_25",
  "fulltext_url": null,
  "id": "9qcmpmm60wraa",
  "issns": [
    "0971-9784"
  ],
  "landing_url": "https://hal.science/hal-05770919v1",
  "language": "en",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.sdv"
    ],
    [
      "hal",
      "1.sdv.mhep"
    ],
    [
      "hal",
      "2.sdv.mhep.csc"
    ],
    [
      "openalex",
      "2704|Blood transfusion and management"
    ]
  ],
  "openalex": "W7159057385",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-07-29",
  "publisher": "Medknow Publications",
  "ris": "https://research.draconitic.com/paper/9qcmpmm60wraa.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:44Z",
      "native_id": "hal-05770919",
      "source": "hal",
      "url": "https://hal.science/hal-05770919v1"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "hal:0.sdv",
      "subfield": "general"
    },
    {
      "field": "medicine",
      "origin": "hal:2.sdv.mhep.csc",
      "subfield": "cardiovascular"
    }
  ],
  "title": "Thrombocytopenia After Cardiac Surgery: A Single-Center Retrospective Study",
  "title_text": "Thrombocytopenia After Cardiac Surgery: A Single-Center Retrospective Study",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:44Z",
  "url": "https://research.draconitic.com/paper/9qcmpmm60wraa",
  "venue": "Annals of Cardiac Anaesthesia",
  "versions": []
}