{
  "abstract": "Background/Objectives: We examined nine biomarkers for acute mesenteric ischemia (AMI) detection, necrosis and postoperative prediction. Methods: PubMed/MEDLINE, the Cochrane Library and indexed citation links were searched on 10 October 2026 without a lower publication-year limit. PubMed and citation searches used an October 2026 publication cutoff. English- and Russian-language clinical reports with at least 10 participants were eligible. Narrative synthesis used QUADAS-2 and diagnostic GRADE. Results: Twenty-nine primary reports were included, with reported cohorts of 18–1479 participants. Cohort overlap and varying tested denominators precluded an unduplicated participant total. Among 28 diagnostic reports, 22 had high index-test risk and 25 had high flow/timing risk. Certainty was very low for eight markers. I-FABP, α-GST and citrulline findings depended on population, assay and timing. D-dimer, lactate, procalcitonin and ischemia-modified albumin lacked intestinal specificity. Urinary I-FABP estimates were imprecise. SM22 supplied association data without diagnostic-performance estimates. Conclusions: No evaluated marker supports reliable stand-alone exclusion of AMI or determination of bowel viability. Complementary panels require prospective validation. The injury diagrams are unvalidated research models.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Hospital Surgery No. 2, Sechenov First Moscow State Medical University ( ), 119048 Moscow, Russia; (Z.B.); (E.K.); (D.P.); (E.T.); (A.S.); (A.K.); (A.N.); (M.I.); (S.N.); (S.M.)",
    "Cardiology Department No. 2, Yudin City Hospital of Moscow, The Patrice Lumumba (RUDN), 117198 Moscow, Russia;"
  ],
  "article_type": "review article",
  "arxiv": null,
  "author_total": 13,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Zelimkhan Berikkhanov"
    },
    {
      "affs": [
        0
      ],
      "name": "Zakhar Akulov"
    },
    {
      "affs": [
        0
      ],
      "name": "Ekaterina Klimova"
    },
    {
      "affs": [
        0
      ],
      "name": "David Pogosyan"
    },
    {
      "affs": [
        0
      ],
      "name": "Evgeniy Tarabrin"
    },
    {
      "affs": [
        0
      ],
      "name": "Alexey Shestakov"
    },
    {
      "affs": [
        0
      ],
      "name": "Aleksey Kotelnikov"
    },
    {
      "affs": [
        0
      ],
      "name": "Andrey Nikolaev"
    },
    {
      "affs": [
        0
      ],
      "name": "Vadim Razumovsky"
    },
    {
      "affs": [
        0
      ],
      "name": "Milena Ivanova"
    },
    {
      "affs": [
        1
      ],
      "name": "Mehrshad Ebrahimnezhad"
    },
    {
      "affs": [
        0
      ],
      "name": "Sara Nourmahal"
    },
    {
      "affs": [
        0
      ],
      "name": "Sergey Muraviev"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/9rzfg9qfy0kj4.bib",
  "cited_by": 0,
  "doi": "10.3390/diagnostics16203360",
  "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13703922/?tool=EBI",
  "id": "9rzfg9qfy0kj4",
  "issns": [
    "2075-4418"
  ],
  "landing_url": "https://europepmc.org/article/PMC/PMC13703922",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "R5-920"
    ],
    [
      "openalex",
      "2746|Abdominal vascular conditions and treatments"
    ]
  ],
  "openalex": "W7222188968",
  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13703922/pdf/?tool=EBI",
  "pmcid": "PMC13703922",
  "pmid": null,
  "published": "2026-10-01",
  "publisher": "MDPI AG",
  "ris": "https://research.draconitic.com/paper/9rzfg9qfy0kj4.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:21:40Z",
      "native_id": "PMC:PMC13703922",
      "source": "europepmc",
      "url": "https://europepmc.org/article/PMC/PMC13703922"
    },
    {
      "first_seen": "2026-10-31T14:21:26Z",
      "native_id": "055046072b19463c821f4926110d79e7",
      "source": "doaj",
      "url": "https://doi.org/10.3390/diagnostics16203360"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2746|Abdominal vascular conditions and treatments",
      "subfield": "surgery"
    }
  ],
  "title": "Biomarkers in Acute Mesenteric Ischemia: A Systematic Review of Diagnostic Performance and Injury-Related Signals",
  "title_text": "Biomarkers in Acute Mesenteric Ischemia: A Systematic Review of Diagnostic Performance and Injury-Related Signals",
  "type": "peer-reviewed",
  "updated_at": "2026-10-31T14:21:26Z",
  "url": "https://research.draconitic.com/paper/9rzfg9qfy0kj4",
  "venue": "Diagnostics (Basel, Switzerland)",
  "versions": []
}