{
  "abstract": "Background: Fulminant myocarditis (FM) is a life-threatening cause of cardiogenic shock. Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is often employed as a bridge to recovery, but data on long-term outcomes and prognostic markers post-discharge remain limited. We described long-term outcomes and explored the association between discharge left ventricular ejection fraction (LVEF) and post-discharge events. Methods: This retrospective, international, multicentre cohort study included adult FM patients who required VA-ECMO and survived to hospital discharge. Patients were stratified by LVEF ≥ 50% or < 50% at discharge. Cox proportional hazards models were used to assess the association between discharge LVEF and the primary composite endpoint of death, heart transplantation, or durable mechanical circulatory support postdischarge. Results: A total of 106 patients from 11 centres were included, with a median age of 43 years (interquartile range 29-57); 42% were male. At discharge, LVEF was ≥ 50% in 69 patients and < 50% in 37 patients. Over a median follow-up of 4.4 years (interquartile range 1.6-7.9), 3 patients (2.8%) experienced the composite outcome (2 deaths, 1 left ventricular assist device implantation). Compared with patients discharged with an LVEF ≥ 50%, those with an LVEF < 50% had a numerically higher risk of the composite endpoint (hazard ratio 2.9, 95% confidence interval 0.19-42.9), although this difference was not statistically significant. Conclusions: Given the low number of postdischarge events, this study was underpowered to assess the prognostic value of discharge LVEF. However, long-term outcomes were favourable among survivors of FM supported with VA-ECMO, regardless of their LVEF at discharge.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 25,
  "authors": [
    {
      "name": "Maria Lambadaris"
    },
    {
      "name": "Julie Vishram-Nielsen"
    },
    {
      "name": "Takahiro Okumura"
    },
    {
      "name": "Yee-Chun Chen"
    },
    {
      "name": "Aristine Cheng"
    },
    {
      "name": "Hsin-Yun Sun"
    },
    {
      "name": "Antonio Loforte"
    },
    {
      "name": "Yasuhide Asaumi"
    },
    {
      "name": "Kenichiro Sawada"
    },
    {
      "name": "Mingjie Huang"
    },
    {
      "name": "Wei Lee"
    },
    {
      "name": "Thomas Fux"
    },
    {
      "name": "Matteo Pozzi"
    },
    {
      "name": "Heather Ross"
    },
    {
      "name": "Finn Gustafsson"
    },
    {
      "name": "Hasse Møller-Sørensen"
    },
    {
      "name": "Albert Ariza-Solé"
    },
    {
      "name": "Mario Senechal"
    },
    {
      "name": "Pierre Yves Turgeon"
    },
    {
      "name": "Manuel Martinez-Selles"
    },
    {
      "name": "Francisco Hernández-Pérez"
    },
    {
      "name": "Roberto Lorusso"
    },
    {
      "name": "Filio Billia"
    },
    {
      "name": "Ana Alba"
    },
    {
      "name": "Julie K.K. Vishram-Nielsen"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/9syagtcfdj0s8.bib",
  "cited_by": 0,
  "doi": "10.1016/j.cjco.2026.03.020",
  "fulltext_url": null,
  "id": "9syagtcfdj0s8",
  "issns": [
    "2589-790X"
  ],
  "landing_url": "https://hal.science/hal-05749372v1",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.sdv"
    ],
    [
      "hal",
      "1.sdv.spee"
    ],
    [
      "openalex",
      "2204|Mechanical Circulatory Support Devices"
    ]
  ],
  "openalex": "W7152054345",
  "pdf_url": "https://www.cjcopen.ca/article/S2589-790X(26)00145-9/pdf",
  "pmcid": null,
  "pmid": "42609710",
  "published": "2026-09-14",
  "publisher": "ScienceDirect - Elsevier",
  "ris": "https://research.draconitic.com/paper/9syagtcfdj0s8.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:34Z",
      "native_id": "hal-05749372",
      "source": "hal",
      "url": "https://hal.science/hal-05749372v1"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "hal:0.sdv",
      "subfield": "general"
    },
    {
      "field": "medicine",
      "origin": "hal:1.sdv.spee",
      "subfield": "epidemiology-public-health"
    }
  ],
  "title": "Long-Term Outcomes in Survivors of Fulminant Myocarditis Supported with Venoarterial Extracorporeal Membrane Oxygenation by Discharge Cardiac Function",
  "title_text": "Long-Term Outcomes in Survivors of Fulminant Myocarditis Supported with Venoarterial Extracorporeal Membrane Oxygenation by Discharge Cardiac Function",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:34Z",
  "url": "https://research.draconitic.com/paper/9syagtcfdj0s8",
  "venue": "Canadian Journal of Cardiology (CJC) : official journal of the Canadian Cardiovascular Society (CCS)",
  "versions": []
}