{
  "abstract": "The local inflammatory response and ongoing viral replication caused by monkeypox virus (MPXV) infection pose severe challenges for clinical treatment. Traditional treatment strategies are unable to achieve the dual goals of virus clearance and tissue repair simultaneously. This study innovatively adopts a hierarchical assembly strategy of “mesoporous carrier anchoring‐gel matrix embedding” to construct a functionalized hydrogel (Polymer@mPDA@Gel). Using mesoporous polydopamine (mPDA) as the exclusive anchoring site to load the polymer, forming an efficient photothermal component, and then embedding this component in a gel matrix with strong adhesion and good biocompatibility. Through hierarchical assembly, the photothermal performance, anti‐inflammatory performance, and biointerfacial properties are precisely integrated to lay the core foundation for its anti‐viral and anti‐inflammatory functions. The functionalized hydrogel constructed realizes targeted clearance of MPXV, regulation of inflammation, and integration of tissue repair, providing a new material technology path and theoretical support for the clinical treatment of MPXV infection.",
  "abstract_shown": true,
  "affiliations": [
    "State Key Laboratory Cultivation Base of Research The Affiliated Stomatological Hospital of Nanjing Medical University Prevention and Treatment for Oral Diseases Jiangsu Province Engineering Research Center of Stomatological Translational Medicine Nanjing Medical University Nanjing China",
    "State Key Laboratory For Diagnosis and Treatment of Severe Zoonotic Infectious Diseases Institute of Zoonosis and College of Veterinary Medicine Key Laboratory for Zoonosis Research of the Ministry of Education Jilin University Changchun China",
    "Changchun Veterinary Research Institute Chinese Academy of Agricultural Sciences Changchun China",
    "Guangdong Basic Research Center of Excellence for Aggregate Science School of Science and Engineering The Chinese University of Hong Kong (Shenzhen) Shenzhen Guangdong China"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 8,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Ming Zhang",
      "orcid": "0000-0002-7191-4198"
    },
    {
      "affs": [
        1,
        2
      ],
      "name": "Jiaxin Tian"
    },
    {
      "affs": [
        1
      ],
      "name": "Xiaolong Zhu"
    },
    {
      "affs": [
        2
      ],
      "name": "Xiao Li",
      "orcid": "0000-0001-7866-3160"
    },
    {
      "affs": [
        2
      ],
      "name": "Xiangshu Qiu"
    },
    {
      "affs": [
        1
      ],
      "name": "Yuanyuan Li",
      "orcid": "0000-0001-8467-9759"
    },
    {
      "affs": [
        3
      ],
      "name": "Ben Zhong Tang",
      "orcid": "0000-0002-0293-964X"
    },
    {
      "affs": [
        1
      ],
      "name": "Ning Shi",
      "orcid": "0000-0002-8149-0210"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/9vgepjr54x1kh.bib",
  "cited_by": 0,
  "doi": "10.1002/advs.76926",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13440193/",
  "id": "9vgepjr54x1kh",
  "issns": [
    "2198-3844"
  ],
  "landing_url": "https://doi.org/10.1002/advs.76926",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Research Article"
    ],
    [
      "openalex",
      "2742|Wound Healing and Treatments"
    ]
  ],
  "openalex": "W7172520691",
  "pdf_url": null,
  "pmcid": "PMC13440193",
  "pmid": "42555190",
  "published": "2026-08-05",
  "publisher": "Wiley",
  "ris": "https://research.draconitic.com/paper/9vgepjr54x1kh.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T12:23:41Z",
      "native_id": "PMC13440193",
      "source": "pmc",
      "url": "https://doi.org/10.1002/advs.76926"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2742|Wound Healing and Treatments",
      "subfield": "general"
    }
  ],
  "title": "Overcoming Transmission Barriers: A Dual‐Functional Adhesive Hydrogel for Direct Monkeypox Virus Neutralization and Wound Healing",
  "title_text": "Overcoming Transmission Barriers: A Dual‐Functional Adhesive Hydrogel for Direct Monkeypox Virus Neutralization and Wound Healing",
  "type": "peer-reviewed",
  "updated_at": "2026-11-01T12:20:48Z",
  "url": "https://research.draconitic.com/paper/9vgepjr54x1kh",
  "venue": "Advanced Science",
  "versions": []
}