{
  "abstract": "This murine iliac AVF model with concurrent renal insufficiency replicates compensated cardiac hypertrophy without heart failure, matching the predominant clinical phenotype in humans unlike existing preclinical models designed to induce high-output heart failure. Cardiomyocyte mitochondrial function was studied for the first time after AVF creation. Female sex was associated with increased respiratory capacity and preserved cardiac function. NAC supplementation showed a trend toward improved mitochondrial function in females.",
  "abstract_shown": true,
  "affiliations": [
    "Division of Vascular Surgery and Endovascular Therapy, University of Florida, Gainesville, Florida, United States",
    "Malcom Randall Veteran Affairs Medical Center, Gainesville, Florida, United States",
    "Department of Applied Physiology and Kinesiology, University of Florida, Gainesville, Florida, United States",
    "Center for Exercise Science, University of Florida, Gainesville, Florida, United States"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 11,
  "authors": [
    {
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        1
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      "name": "Erik M. Anderson"
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    {
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      "name": "Victoria R. Palzkill"
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    {
      "affs": [
        2
      ],
      "name": "Kyoungrae Kim"
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    {
      "affs": [
        0,
        1
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      "name": "Brian Fazzone"
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    {
      "affs": [
        2
      ],
      "name": "Eric M. Kunz"
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    {
      "affs": [
        0,
        1
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      "name": "Qiongyao Hu"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Yong He"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Kerri A. O’Malley"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Scott A. Berceli"
    },
    {
      "affs": [
        2,
        3
      ],
      "name": "Terence E. Ryan"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Salvatore T. Scali"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/9x7efskc4hxj7.bib",
  "cited_by": 0,
  "doi": "10.1152/ajpheart.90253.2026",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13723068/",
  "id": "9x7efskc4hxj7",
  "issns": [
    "0363-6135",
    "1522-1539"
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  "landing_url": "https://doi.org/10.1152/ajpheart.90253.2026",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Article"
    ],
    [
      "openalex",
      "3604|Central Venous Catheters and Hemodialysis"
    ]
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  "openalex": "W7220423852",
  "pdf_url": null,
  "pmcid": "PMC13723068",
  "pmid": "42832374",
  "published": "2026-10-05",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/9x7efskc4hxj7.ris",
  "sources": [
    {
      "first_seen": "2026-11-04T12:21:44Z",
      "native_id": "PMC13723068",
      "source": "pmc",
      "url": "https://doi.org/10.1152/ajpheart.90253.2026"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "journal-openalex:2705|Cardiac electrophysiology and arrhythmias",
      "subfield": "cardiovascular"
    }
  ],
  "title": "Cardiac Adaptation in a Murine Iliac Arteriovenous Fistula Model and the Impact of Sex and N-Acetylcysteine Supplementation",
  "title_text": "Cardiac Adaptation in a Murine Iliac Arteriovenous Fistula Model and the Impact of Sex and N-Acetylcysteine Supplementation",
  "type": "peer-reviewed",
  "updated_at": "2026-11-04T12:21:44Z",
  "url": "https://research.draconitic.com/paper/9x7efskc4hxj7",
  "venue": "American journal of physiology. Heart and circulatory physiology",
  "versions": []
}