{
  "abstract": "Background\n\nProsthetic aortic infection involving composite roots and frozen elephant trunk components presents an extraordinary challenge with high mortality. We present a complex aortic reconstruction using custom bovine pericardial conduits.Case summary\n\nA 55-year-old man with a history of a redo Bentall procedure and frozen elephant trunk implantation presented with extensive pan-aortic prosthetic infection, systemic septic emboli, and acute intracranial hemorrhage. Surgery focused on radical debridement and complete extrication of all synthetic material. The aortic root, ascending aorta, arch, and supra-aortic branches were entirely reconstructed using 4 intraoperatively hand-fashioned bovine pericardial tube grafts, creating a classic elephant trunk assembly. The patient was extubated on the day of surgery, discharged on day 7 without neurologic deficits, and remained infection-free at 3 months.Discussion\n\nRadical excision and total aortic reconstruction using hand-made bovine pericardial grafts provide a completely biological, infection-resistant alternative for treating these highly complex conditions.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Thoracic & Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio, USA. Electronic address: PASICM@ccf.org.",
    "Department of Thoracic & Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio, USA."
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Miralem Pasic"
    },
    {
      "affs": [
        1
      ],
      "name": "Sanjay Chaubey"
    },
    {
      "affs": [
        1
      ],
      "name": "Kang An"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/9xbt7rvvz3876.bib",
  "cited_by": 0,
  "doi": "10.1016/j.jaccas.2026.110322",
  "fulltext_url": "https://europepmc.org/articles/PMC13669872",
  "id": "9xbt7rvvz3876",
  "issns": [
    "2666-0849"
  ],
  "landing_url": "https://europepmc.org/article/MED/42847578",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2746|Infectious Aortic and Vascular Conditions"
    ]
  ],
  "openalex": "W7220868823",
  "pdf_url": "https://europepmc.org/articles/PMC13669872?pdf=render",
  "pmcid": "PMC13669872",
  "pmid": "42847578",
  "published": "2026-10-01",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/9xbt7rvvz3876.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:18:10Z",
      "native_id": "MED:42847578",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42847578"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2746|Infectious Aortic and Vascular Conditions",
      "subfield": "surgery"
    }
  ],
  "title": "Total Thoracic Aortic \"Pericardialization\" for Multilevel Prosthetic Graft Infection.",
  "title_text": "Total Thoracic Aortic \"Pericardialization\" for Multilevel Prosthetic Graft Infection.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:18:10Z",
  "url": "https://research.draconitic.com/paper/9xbt7rvvz3876",
  "venue": "JACC. Case reports",
  "versions": []
}