{
  "abstract": "Background:: This bibliometric study characterized the research landscape of literature jointly addressing remimazolam and midazolam from January 2016 through September 2025, with emphasis on publication trends, collaboration patterns, intellectual structure, and emerging research topics.\n\nMethods:: Records published from January 1, 2016 through September 30, 2025 were retrieved from the Web of Science Core Collection on October 30, 2025 using a predefined topic search designed to identify publications in which remimazolam and midazolam were jointly represented. After eligibility screening, 349 publications were analyzed using CiteSpace, VOSviewer, and Bibliometrix to evaluate publication trends, collaboration networks, co-citation patterns, and keyword evolution.\n\nResults:: Publication output increased markedly over the study period. China contributed the largest number of publications, followed by Japan, South Korea, and the United States. Major research themes included pharmacokinetics, safety, efficacy, and procedural sedation. Recent keyword signals included flumazenil, risk, and upper gastrointestinal endoscopy. Research productivity was concentrated within a limited number of journals and institutions, whereas international co-authorship was limited in this dataset.\n\nConclusion:: Research jointly addressing remimazolam and midazolam expanded markedly during the study period and was geographically concentrated, with prominent attention to pharmacokinetics, safety, efficacy, and procedural sedation. These findings provide a structured overview of how the field has evolved and highlight priorities for multinational collaboration, direct comparative studies, and patient-specific dosing research.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Anesthesiology, The Third People’s Hospital of Longgang, Clinical Institute of Shantou University Medical College (The Third People’s Hospital of Longgang District Shenzhen), Guangdong, China",
    "First School of Clinical Medicine, Guangdong Pharmaceutical University, Guangdong, China."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Yu Liu"
    },
    {
      "affs": [
        0
      ],
      "name": "Liang Cong"
    },
    {
      "affs": [
        0
      ],
      "name": "Shengzhen Luo"
    },
    {
      "affs": [
        1
      ],
      "name": "Yuying Ma"
    },
    {
      "affs": [
        1
      ],
      "name": "Hui Xiao"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Yongwang Li",
      "orcid": "0000-0002-6330-8614"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/9ypps6ds6axhq.bib",
  "cited_by": 0,
  "doi": "10.1097/md.0000000000051418",
  "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13727237/?tool=EBI",
  "id": "9ypps6ds6axhq",
  "issns": [
    "0304-5412",
    "1536-5964",
    "0025-7974"
  ],
  "landing_url": "https://europepmc.org/article/PMC/PMC13727237",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "3300"
    ],
    [
      "heading",
      "Bibliometric Review"
    ],
    [
      "heading",
      "Research Article"
    ]
  ],
  "openalex": null,
  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13727237/pdf/?tool=EBI",
  "pmcid": "PMC13727237",
  "pmid": null,
  "published": "2026-10-30",
  "publisher": "Wolters Kluwer Health",
  "ris": "https://research.draconitic.com/paper/9ypps6ds6axhq.ris",
  "sources": [
    {
      "first_seen": "2026-11-03T15:20:51Z",
      "native_id": "PMC:PMC13727237",
      "source": "europepmc",
      "url": "https://europepmc.org/article/PMC/PMC13727237"
    },
    {
      "first_seen": "2026-11-05T12:23:21Z",
      "native_id": "PMC13727237",
      "source": "pmc",
      "url": "https://doi.org/10.1097/md.0000000000051418"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "journal-openalex:F27",
      "subfield": "general"
    }
  ],
  "title": "Research trends and hotspots in publications jointly addressing remimazolam and midazolam : A bibliometric analysis, 2016–2025",
  "title_text": "Research trends and hotspots in publications jointly addressing remimazolam and midazolam : A bibliometric analysis, 2016–2025",
  "type": "peer-reviewed",
  "updated_at": "2026-11-06T12:22:57Z",
  "url": "https://research.draconitic.com/paper/9ypps6ds6axhq",
  "venue": "Medicine",
  "versions": []
}