{
  "abstract": "Mitogen-activated protein kinase (MAPK/MPK) cascades are conserved signaling modules that play crucial roles in plant growth, reproduction, and responses to biotic and abiotic stresses. Many breakthroughs have been made recently in understanding the functional and regulatory mechanisms involving MAPK cascades in plant immunity. In this review, we summarize the conserved composition and activation of MAPK cascades and update advances in understanding the molecular mechanisms by which plants maintain or inhibit MAPK activation. We also highlight the functional links between MAPK activation and other immune events, suggesting crosstalk in the plant immune signaling network. Furthermore, we outline the strategies by which pathogen effectors inhibit plant immunity by manipulating MAPK signaling and illuminate the contribution of MAPK cascades to effector-triggered immunity. Overall, this review provides major evidence for understanding the importance and complexity of MAPK signaling and reveals that the MAPK cascade serves as an essential signaling hub in activating plant immunity.",
  "abstract_shown": true,
  "affiliations": [
    "State Key Laboratory of Agricultural and Forestry Biosecurity, Key Laboratory of Ministry of Education for Genetics, Breeding and Multiple Utilization of Crops, Plant Immunity Center, Haixia Institute of Science and Technology Fujian Agriculture and Forestry University Fuzhou 350002 China",
    "Fujian Provincial Key Laboratory of Crop Breeding by Design Fujian Agriculture and Forestry University Fuzhou 350002 China"
  ],
  "article_type": "review",
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Guitao Zhong",
      "orcid": "0000-0003-1564-9630"
    },
    {
      "affs": [
        0
      ],
      "name": "Zhanchun Wang",
      "orcid": "0009-0000-6272-0060"
    },
    {
      "affs": [
        0
      ],
      "name": "Dingzhong Tang",
      "orcid": "0000-0001-8850-8754"
    },
    {
      "affs": [
        1,
        0
      ],
      "name": "Wei Wang",
      "orcid": "0000-0001-9027-1549"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/9zr9456m3xah3.bib",
  "cited_by": 9,
  "doi": "10.1111/jipb.70306",
  "fulltext_url": null,
  "id": "9zr9456m3xah3",
  "issns": [
    "0577-7496",
    "1672-9072",
    "1744-7909"
  ],
  "landing_url": "https://doi.org/10.1111/jipb.70306",
  "language": "en",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1110|Plant-Microbe Interactions and Immunity"
    ]
  ],
  "openalex": "W7162440598",
  "pdf_url": null,
  "pmcid": "PMC13446642",
  "pmid": "42186123",
  "published": "2026-05-25",
  "publisher": "Wiley",
  "ris": "https://research.draconitic.com/paper/9zr9456m3xah3.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:26:50Z",
      "native_id": "W7162440598",
      "source": "openalex",
      "url": "https://doi.org/10.1111/jipb.70306"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:1110|Plant-Microbe Interactions and Immunity",
      "subfield": "plant-biology"
    }
  ],
  "title": "Decoding MAPK cascades in plant immunity: Activation, regulation, integration, and pathogen manipulation",
  "title_text": "Decoding MAPK cascades in plant immunity: Activation, regulation, integration, and pathogen manipulation",
  "type": "peer-reviewed",
  "updated_at": "2026-11-09T13:21:08Z",
  "url": "https://research.draconitic.com/paper/9zr9456m3xah3",
  "venue": "Journal of Integrative Plant Biology",
  "versions": []
}