{
  "abstract": "Human Y chromosome satellites vary widely but remain difficult to measure in large cohorts. In response, we developed Yruler, which uses pangenome assemblies to measure satellite lengths, composition and Y dosage from sequencing reads without alignment. Analyses reveal centromere-length differences between related lineages, extend observations of short non-centromeric arrays across a lineage, and show unequal component variability and composition changes with heterochromatin length within lineages. Yruler brings satellite variation into population-scale phenotype studies.",
  "abstract_shown": true,
  "affiliations": [
    "Translational Genomics Research Institute"
  ],
  "article_type": "New results",
  "arxiv": null,
  "author_total": 2,
  "authors": [
    {
      "name": "A. Ortigas-Vasquez"
    },
    {
      "affs": [
        0
      ],
      "name": "A. Guarracino"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/a0pra0rq6xm8w.bib",
  "cited_by": 0,
  "doi": "10.64898/2026.11.04.764422",
  "fulltext_url": "https://www.biorxiv.org/content/10.64898/2026.11.04.764422v1.full",
  "id": "a0pra0rq6xm8w",
  "issns": [],
  "landing_url": "https://www.biorxiv.org/content/10.64898/2026.11.04.764422v1",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "biorxiv",
      "genomics"
    ]
  ],
  "openalex": null,
  "pdf_url": "https://www.biorxiv.org/content/10.64898/2026.11.04.764422v1.full.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-11-04",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/a0pra0rq6xm8w.ris",
  "sources": [
    {
      "first_seen": "2026-11-06T12:21:00Z",
      "native_id": "10.64898/2026.11.04.764422",
      "source": "biorxiv",
      "url": "https://www.biorxiv.org/content/10.64898/2026.11.04.764422v1"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "biorxiv:genomics",
      "subfield": "genetics-genomics"
    }
  ],
  "title": "Measuring satellite arrays of the human Y chromosome from sequencing reads",
  "title_text": "Measuring satellite arrays of the human Y chromosome from sequencing reads",
  "type": "preprint",
  "updated_at": "2026-11-08T00:20:56Z",
  "url": "https://research.draconitic.com/paper/a0pra0rq6xm8w",
  "venue": "bioRxiv",
  "versions": []
}