{
  "abstract": "Chirality appears in many molecules, crystals, and nanostructures and plays an important role in their physicochemical and biological functions. Because biological systems exhibit a chiral bias, they respond differently to each chiral enantiomer. Therefore, it is very important to develop methods or devices that can discriminate the enantiomers easily. Metallic nanostructures such as nanoparticles, nanorods, and mesoporous films exhibit significantly enhanced optical responses due to localized surface plasmon resonance. The optical properties of these nanostructures are highly dependent on their size, shape, and elemental composition, all of which can be precisely controlled through optimized chemical synthesis. In this study, we developed a hierarchical nanostructure of chiral Au nanostructures on Au coral structures, which were synthesized on transparent conductive oxide substrates using only electrochemical techniques. By considering both the substitution of chloride ions in [AuCl4]− with cysteine in the electrolyte solution and the subsequent reduction of the Au(III) complexes, we successfully controlled the morphology of the Au nanostructures, which exhibit circular dichroism. Furthermore, we explored the potential for chiral discrimination using these substrates. The hierarchical chiral Au nanostructures on Au coral structures enhanced the SERS intensity relative to Au corals alone and produced enantiomer‐dependent SERS responses for L‐ and D‐phenylalanine, demonstrating their potential for chiral discrimination.",
  "abstract_shown": true,
  "affiliations": [
    "Comprehensive Research Organization Waseda University Tokyo Japan",
    "Faculty of Science and Engineering Waseda University Tokyo Japan",
    "International Center for Materials Nanoarchitectonics (WPI‐MANA) National Institute for Materials Science (NIMS) Tsukuba Ibaraki Japan",
    "Department of Materials Science and Engineering School of Engineering Nagoya University Nagoya Japan",
    "Australian Institute for Bioengineering and Nanotechnology (AIBN) The University of Queensland (UQ) Brisbane QLD Australia",
    "Research Organization for Nano & Life Innovation Waseda University Tokyo Japan"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 8,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Kenta Nakagawa",
      "orcid": "0000-0002-0577-537X"
    },
    {
      "affs": [
        1
      ],
      "name": "Junhe Wang"
    },
    {
      "affs": [
        1
      ],
      "name": "Tianji Zhang"
    },
    {
      "affs": [
        1
      ],
      "name": "Yuta Shiga"
    },
    {
      "affs": [
        2
      ],
      "name": "Olga Guselnikova"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Takuya Nakanishi",
      "orcid": "0000-0002-1172-718X"
    },
    {
      "affs": [
        2,
        3,
        4
      ],
      "name": "Yusuke Yamauchi",
      "orcid": "0000-0001-7854-927X"
    },
    {
      "affs": [
        0,
        1,
        5
      ],
      "name": "Toru Asahi"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/a4gb061g2a5t2.bib",
  "cited_by": 0,
  "doi": "10.1002/smll.75471",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13725400/",
  "id": "a4gb061g2a5t2",
  "issns": [
    "1613-6810",
    "1613-6829"
  ],
  "landing_url": "https://doi.org/10.1002/smll.75471",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Research Article"
    ],
    [
      "openalex",
      "2504|Gold and Silver Nanoparticles Synthesis and Applications"
    ]
  ],
  "openalex": "W7208745975",
  "pdf_url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/smll.75471",
  "pmcid": "PMC13725400",
  "pmid": "42693740",
  "published": "2026-09-03",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/a4gb061g2a5t2.ris",
  "sources": [
    {
      "first_seen": "2026-11-04T12:23:48Z",
      "native_id": "PMC13725400",
      "source": "pmc",
      "url": "https://doi.org/10.1002/smll.75471"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:2504|Gold and Silver Nanoparticles Synthesis and Applications",
      "subfield": "materials-polymers"
    }
  ],
  "title": "Synthesis of Chiral Gold Nanostructures on Gold‐Coral‐Coated Transparent Conductive Oxide Substrates via [AuCl4]– and Cysteine Interactions for Enhanced Chiral Sensing",
  "title_text": "Synthesis of Chiral Gold Nanostructures on Gold‐Coral‐Coated Transparent Conductive Oxide Substrates via [AuCl4]– and Cysteine Interactions for Enhanced Chiral Sensing",
  "type": "peer-reviewed",
  "updated_at": "2026-11-06T12:21:40Z",
  "url": "https://research.draconitic.com/paper/a4gb061g2a5t2",
  "venue": "Small (Weinheim an Der Bergstrasse, Germany)",
  "versions": []
}