{
  "abstract": "Objective.To investigate the morphological changes in liver tissue resulting from the local application of bipolar and ultrasonic electrocoagulators in an experimental setting.\n\nMateria ls and methods. The study was conducted on two male pigs that underwent laparoscopic gallbladder removal with coagulation of the gallbladder bed; in one animal, this was performed using a LigaSure bipolar electrocoagulator, and in the other, using a Harmonic ultrasonic instrument. For microscopic examination, liver tissue samples were taken from the coagulation zone together with the adjacent macroscopically unchanged parenchyma.\n\nResults. A comparative analysis of the morphological changes in liver tissue induced by the LigaSure bipolar electrocoagulator and the Harmonic ultrasonic scalpel revealed that the mechanisms by which haemostasis is achieved and the morphological changes in the parenchyma of this organ are fundamentally different. When the Harmonic coagulator is used, a clearly defined zone of coagulative necrosis is formed, with a ‘melting’ effect on collagenous structures, which ensures reliable haemostasis and cholestasis. Bipolar coagulation effectively complements this process, ensuring stable haemostasis through deep thermal occlusion of the vessels. Morphological findings confirm minimal damage to surrounding tissues, which allows these methods to be recommended for precision procedures on parenchymal organs, including the liver.\n\nConclusions. A comparative analysis has demonstrated that the use of high-energy bipolar (LigaSure) and ultrasonic (Harmonic) coagulators is pathomorphologically justified and a priority in liver surgery, as they minimise the area of delayed necrosis and stimulate an early regenerative response in hepatocytes.",
  "abstract_shown": true,
  "affiliations": [
    "Poltava State Medical University"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "V. Y. Korniychuk",
      "orcid": "0009-0002-9537-4568"
    },
    {
      "affs": [
        0
      ],
      "name": "M. O. Dudchenko",
      "orcid": "0009-0007-8729-0547"
    },
    {
      "affs": [
        0
      ],
      "name": "V. I. Liakhovskyi",
      "orcid": "0000-0003-1551-4891"
    },
    {
      "affs": [
        0
      ],
      "name": "M. I. Kravtsiv",
      "orcid": "0000-0002-9602-4714"
    },
    {
      "affs": [
        0
      ],
      "name": "B. M. Fylenko",
      "orcid": "0000-0002-8659-2267"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/a4ge12jjqf987.bib",
  "cited_by": 0,
  "doi": "10.26779/2786-832x.2026.5.80",
  "fulltext_url": "https://hirurgiya.com.ua/index.php/journal/article/view/1366",
  "id": "a4ge12jjqf987",
  "issns": [
    "2786-832X",
    "2786-8311"
  ],
  "landing_url": "https://doi.org/10.26779/2786-832x.2026.5.80",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "RD1-811"
    ],
    [
      "openalex",
      "2720|Hemostasis and retained surgical items"
    ]
  ],
  "openalex": "W7223267049",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-23",
  "publisher": "Liga-Inform ltd.",
  "ris": "https://research.draconitic.com/paper/a4ge12jjqf987.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:43:58Z",
      "native_id": "ae48113dbe5642b897e04485484c0a74",
      "source": "doaj",
      "url": "https://doi.org/10.26779/2786-832x.2026.5.80"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "lcc:RD1-811",
      "subfield": "surgery"
    }
  ],
  "title": "Morphological changes in liver tissue induced by high-frequency and ultrasonic coagulation in an experimental study",
  "title_text": "Morphological changes in liver tissue induced by high-frequency and ultrasonic coagulation in an experimental study",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:43:58Z",
  "url": "https://research.draconitic.com/paper/a4ge12jjqf987",
  "venue": "Український журнал клінічної хірургії",
  "versions": []
}