{
  "abstract": "Allergic rhinitis (AR) is highly prevalent in children and adolescents and impairs quality of life, sleep, and school performance, while also worsening asthma control. The last EAACI position paper on pediatric AR was published in 2013. Significant scientific advancements, including the new ARIA 2026 guidelines, necessitate an updated national framework. This Italian Society of Pediatric Allergology and Immunology (SIAIP) document aims to provide an evidence-based age-specific framework for the diagnosis, classification, and practical management of AR in children and adolescents, while addressing the limitations of existing less granular guidelines. A dedicated SIAIP experts' board reviewed current scientific literature, integrated updated epidemiological data, revised classifications, and emerging evidence on allergen immunotherapy. It incorporates the ARIA 2026 guidelines and adapts them to the clinical challenges and age-specific considerations relevant to pediatric practice. The board of qualified experts and a panel of multidisciplinary clinicians discussed and approved the document. This document covers the epidemiology, pathophysiology, and diagnosis of AR in children and adolescents. It provides detailed stepwise pharmacologic recommendations and discusses the role of allergen immunotherapy (AIT), taking age-specific factors and complementary therapies into account. Evidence-based statements and practical management algorithms aim to optimize diagnostic pathways and therapeutic interventions. This SIAIP document offers clinically actionable guidance for healthcare professionals. It emphasizes early diagnosis, stepwise treatment strategies, and the disease-modifying role of AIT, aiming to enhance diagnostic accuracy, streamline management, and ultimately improve the long-term health and well-being of affected children and adolescents.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Medicine and Health Sciences, University of Molise, Campobasso, Italy.",
    "Pediatric Unit, Department of Clinical, Surgical, Diagnostic, and Pediatric Sciences, University of Pavia, Pavia, Italy.",
    "Pediatrics, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.",
    "Department of Woman and Child and General and Specialized Surgery, University of Campania Luigi Vanvitelli, Naples, Italy.",
    "Unit of Pediatrics, Department of Human Pathology in Adult and Developmental Age \"Gaetano Barresi\", University of Messina, Messina, Italy.",
    "Allergy Center, IRCCS Istituto Giannina Gaslini, Genoa, Italy.",
    "Pediatric Department, La Sapienza University, Rome, Italy."
  ],
  "article_type": "review article",
  "arxiv": null,
  "author_total": 8,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Giorgio Ciprandi",
      "orcid": "0000-0001-7016-8421"
    },
    {
      "affs": [
        1,
        2
      ],
      "name": "Amelia Licari",
      "orcid": "0000-0002-1773-6482"
    },
    {
      "affs": [
        3
      ],
      "name": "Cristiana Indolfi",
      "orcid": "0000-0002-9513-193X"
    },
    {
      "affs": [
        4
      ],
      "name": "Sara Manti"
    },
    {
      "affs": [
        3
      ],
      "name": "Michele Miraglia Del Giudice",
      "orcid": "0000-0002-8369-5957"
    },
    {
      "affs": [
        5
      ],
      "name": "Maria Angela Tosca"
    },
    {
      "affs": [
        6
      ],
      "name": "Anna Maria Zicari"
    },
    {
      "affs": [
        1,
        2
      ],
      "name": "Gianluigi Marseglia"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/a51w6dk6phgdt.bib",
  "cited_by": 0,
  "doi": "10.1002/clt2.70218",
  "fulltext_url": "https://europepmc.org/articles/PMC13744421",
  "id": "a51w6dk6phgdt",
  "issns": [
    "2045-7022"
  ],
  "landing_url": "https://europepmc.org/article/MED/42998301",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2723|Allergic Rhinitis and Sensitization"
    ]
  ],
  "openalex": "W7225463050",
  "pdf_url": "https://europepmc.org/articles/PMC13744421?pdf=render",
  "pmcid": "PMC13744421",
  "pmid": "42998301",
  "published": "2026-11-01",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/a51w6dk6phgdt.ris",
  "sources": [
    {
      "first_seen": "2026-11-09T15:20:34Z",
      "native_id": "MED:42998301",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42998301"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:2723|Allergic Rhinitis and Sensitization",
      "subfield": "immunology"
    }
  ],
  "title": "A Current Evidence Review From the Italian Society of Pediatric Allergology and Immunology (SIAIP) on Practical Management of Allergic Rhinitis in Children and Adolescents.",
  "title_text": "A Current Evidence Review From the Italian Society of Pediatric Allergology and Immunology (SIAIP) on Practical Management of Allergic Rhinitis in Children and Adolescents.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-09T15:20:34Z",
  "url": "https://research.draconitic.com/paper/a51w6dk6phgdt",
  "venue": "Clinical and translational allergy",
  "versions": []
}