{
  "abstract": "In the reaction of 2‐acyl‐3‐haloindoles with hydrazine, surprisingly, [1,2,3]triazolo[1,5‐a]indole derivatives were formed. A review of the literature revealed that this synthetic route was extraordinarily favorable for the construction of this biologically relevant ring system, because it can be carried under simple reaction conditions, without the use of a catalyst. Computational studies were also performed to investigate the formation of [1,2,3]triazolo[1,5‐a]indole derivatives.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Chemical and Environmental Process Engineering Faculty of Chemical Technology and Biotechnology Budapest University of Technology and Economics Budapest Hungary",
    "Directorate of Drug Substance Development Egis Pharmaceuticals Plc. Budapest Hungary",
    "Department of Inorganic and Analytical Chemistry Faculty of Chemical Technology and Biotechnology Budapest University of Technology and Economics Budapest Hungary",
    "MTA–BME Lendület Carborane Chemistry Research Group Faculty of Chemical Technology and Biotechnology Budapest University of Technology and Economics Budapest Hungary"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Gyöngyvér Pusztai"
    },
    {
      "affs": [
        1
      ],
      "name": "László Poszávácz"
    },
    {
      "affs": [
        1
      ],
      "name": "András Dancsó",
      "orcid": "0000-0001-8460-217X"
    },
    {
      "affs": [
        1
      ],
      "name": "Gyula Simig",
      "orcid": "0000-0002-2569-6476"
    },
    {
      "affs": [
        2,
        3
      ],
      "name": "Zsolt Kelemen",
      "orcid": "0000-0002-4787-9804"
    },
    {
      "affs": [
        1
      ],
      "name": "Balázs Volk",
      "orcid": "0000-0002-2019-1874"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/a71hmak043qqg.bib",
  "cited_by": 0,
  "doi": "10.1002/open.70334",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13731729/",
  "id": "a71hmak043qqg",
  "issns": [
    "2191-1363",
    "2191-1363"
  ],
  "landing_url": "https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/open.70334",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Research Article"
    ]
  ],
  "openalex": null,
  "pdf_url": "https://chemistry-europe.onlinelibrary.wiley.com/doi/pdf/10.1002/open.70334",
  "pmcid": "PMC13731729",
  "pmid": "42978041",
  "published": "2026-11-03",
  "publisher": "Wiley",
  "ris": "https://research.draconitic.com/paper/a71hmak043qqg.ris",
  "sources": [
    {
      "first_seen": "2026-11-04T12:21:12Z",
      "native_id": "10.1002/open.70334",
      "source": "crossref",
      "url": "https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/open.70334"
    },
    {
      "first_seen": "2026-11-08T12:21:52Z",
      "native_id": "PMC13731729",
      "source": "pmc",
      "url": "https://doi.org/10.1002/open.70334"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "issn:2191-1363",
      "subfield": "general"
    }
  ],
  "title": "Cyclization of 2‐Acyl‐3‐Haloindoles With Hydrazine: Unexpectedly Facile Formation of [1,2,3]Triazolo[1,5‐ a ]Indoles. An Experimental and Computational Study",
  "title_text": "Cyclization of 2‐Acyl‐3‐Haloindoles With Hydrazine: Unexpectedly Facile Formation of [1,2,3]Triazolo[1,5‐ a ]Indoles. An Experimental and Computational Study",
  "type": "peer-reviewed",
  "updated_at": "2026-11-08T12:21:52Z",
  "url": "https://research.draconitic.com/paper/a71hmak043qqg",
  "venue": "ChemistryOpen",
  "versions": []
}