{
  "abstract": "Higher olefins, specifically n-hexadecene (C16H32), are essential raw materials in the cosmetic industry, particularly for the synthesis of biodegradable surfactants. However, resolving the complex landscape of positional and geometric (cis/trans) isomers remains a significant analytical challenge. This study presents a comprehensive evaluation of gas chromatography (GC) stationary phase selectivity for the separation of n-hexadecene isomers and stereoisomers. By comparing non-polar (Rxi-5Sil MS), polar (ZB-WAX plus) and highly polar (SP-2560) columns against historical stationary phases, we identified a distinct ‘crossover’ elution trend on non-polar phases. Conversely, the highly polar SP-2560 demonstrated superior selectivity, consistently eluting trans-isomers before their cis-counterparts across all positional n-hexadecene isomers. Notably, this research is the first to utilize synthesized and NMR-characterized analytical standards to establish Retention Indices (RI) for these specific isomers. By eliminating the ambiguity associated with historical isomer mixtures, this work provides a rigorous benchmark for future analysis of complex C16 olefins-based raw materials.",
  "abstract_shown": true,
  "affiliations": [
    "L’Oréal Research and Innovation"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "M. Isabel A. Pinto"
    },
    {
      "affs": [
        0
      ],
      "name": "Tanguy Desbrosses--Lacombre"
    },
    {
      "affs": [
        0
      ],
      "name": "Priscilla Riva"
    },
    {
      "affs": [
        0
      ],
      "name": "Nadège Garçonnat"
    },
    {
      "affs": [
        0
      ],
      "name": "Alexis Dubuis"
    },
    {
      "affs": [
        0
      ],
      "name": "Natali Stojiljkovic"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/a88yrfejx9qqt.bib",
  "cited_by": 0,
  "doi": "10.1038/s41598-026-69681-2",
  "fulltext_url": "https://doi.org/10.1038/s41598-026-69681-2",
  "id": "a88yrfejx9qqt",
  "issns": [
    "2045-2322"
  ],
  "landing_url": "https://doi.org/10.1038/s41598-026-69681-2",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "Q"
    ],
    [
      "lcc",
      "R"
    ],
    [
      "openalex",
      "1607|Analytical Chemistry and Chromatography"
    ]
  ],
  "openalex": "W7211907643",
  "pdf_url": "https://www.nature.com/articles/s41598-026-69681-2_reference.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-01",
  "publisher": "Nature Portfolio",
  "ris": "https://research.draconitic.com/paper/a88yrfejx9qqt.ris",
  "sources": [
    {
      "first_seen": "2026-11-01T14:21:17Z",
      "native_id": "0360e50c55c24f6582addf454bc2a701",
      "source": "doaj",
      "url": "https://doi.org/10.1038/s41598-026-69681-2"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1607|Analytical Chemistry and Chromatography",
      "subfield": "physical"
    }
  ],
  "title": "Evaluating stationary phase selectivity for retention index determination and resolution of n-hexadecene isomers",
  "title_text": "Evaluating stationary phase selectivity for retention index determination and resolution of n-hexadecene isomers",
  "type": "peer-reviewed",
  "updated_at": "2026-11-03T14:20:45Z",
  "url": "https://research.draconitic.com/paper/a88yrfejx9qqt",
  "venue": "Scientific Reports",
  "versions": []
}