{
  "abstract": "Objective: The Soci´et´e française d'anesth´ esie et de r´ eanimation (Sfar, the French society of anaesthesia and intensive care) and the Soci´et´e française d'allergologie (SFA, the French society of allergy) have collaborated to propose guidelines for the diagnosis and management of perioperative immediate hypersensitivity reactions. Design: A group of 23 French experts from the Sfar and the SFA was assembled. Any potential conflicts of interest were officially declared at the outset of the recommendations development process, which was conducted independently of any industry funding. The authors used the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology to assess the level of evidence in the literature. Methods: Four fields were defined: (1) Diagnostic assessment of perioperative immediate hypersensitivity reactions; (2) Risk factors for perioperative immediate hypersensitivity reactions; (3) Treatment in scheduled and emergency situations and; (4) Treatment of perioperative immediate hypersensitivity reactions. For each field, the aim of the recommendations was to answer questions formulated by the experts according to the Population, Intervention, Comparison, Outcome (PICO) model. Based on these questions, an extensive literature search covering the last 24 years was carried out using predefined keywords according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) recommendations. The level of evidence was analysed using the GRADE method. The recommendations were formulated using the GRADE method, then voted on by all the experts using the GRADE grid method. Results: The experts' summary work and the application of the GRADE method resulted in 70 recommendations concerning 31 questions. After three rounds of voting and several amendments, strong agreement was reached on 70 recommendations. Of these recommendations, six had a high level of evidence (six GRADE 1), 16 had a low level of evidence (16 GRADE 2) and 48 were expert opinions. Finally, for one question, no recommendation could be made. Conclusion: There was strong agreement among the experts to formulate recommendations aimed at providing a benchmark for the diagnosis and management of perioperative immediate hypersensitivity reactions.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 26,
  "authors": [
    {
      "name": "Paul Michel Mertès"
    },
    {
      "name": "Anca Chiriac"
    },
    {
      "name": "Charles Tacquard"
    },
    {
      "name": "Alain Facon"
    },
    {
      "name": "Sébastien Franchina"
    },
    {
      "name": "Aurélie Gouel-Chéron"
    },
    {
      "name": "Caroline Klingebiel"
    },
    {
      "name": "Corinne Lejus-Bourdeau"
    },
    {
      "name": "Diane Le Quang"
    },
    {
      "name": "Nidhal Leray-Touati"
    },
    {
      "name": "Dan Longrois"
    },
    {
      "name": "Claire Mailhol"
    },
    {
      "name": "Jean-Marc Malinosvsky"
    },
    {
      "name": "Isabelle Migueres"
    },
    {
      "name": "Moise Michel"
    },
    {
      "name": "Martine Morisset"
    },
    {
      "name": "Catherine Neukirch"
    },
    {
      "name": "Diane Pelletier de Chambure"
    },
    {
      "name": "Christelle Pellerin"
    },
    {
      "name": "Mélanie Perquin"
    },
    {
      "name": "Guillaume Pouessel"
    },
    {
      "name": "Cécile Rochefort-Morel"
    },
    {
      "name": "Elleni-Sofia Vaia"
    },
    {
      "name": "Joana Vitte"
    },
    {
      "name": "Anaïs Caillard"
    },
    {
      "name": "Pascal Demoly"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/a96cv47q714jg.bib",
  "cited_by": 0,
  "doi": "10.1016/j.jahd.2026.100068",
  "fulltext_url": null,
  "id": "a96cv47q714jg",
  "issns": [
    "2950-3124",
    "2950-3124"
  ],
  "landing_url": "https://univ-reims.hal.science/hal-05735251v1",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.sdv"
    ],
    [
      "openalex",
      "2736|Drug-Induced Adverse Reactions"
    ]
  ],
  "openalex": "W7162809539",
  "pdf_url": "https://univ-reims.hal.science/hal-05735251/document",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-02",
  "publisher": "Elsevier",
  "ris": "https://research.draconitic.com/paper/a96cv47q714jg.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:24Z",
      "native_id": "hal-05735251",
      "source": "hal",
      "url": "https://univ-reims.hal.science/hal-05735251v1"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2736|Drug-Induced Adverse Reactions",
      "subfield": "pharmacology-toxicology"
    }
  ],
  "title": "Guidelines on the diagnosis and management of perioperative immediate hypersensitivity reactions 2025",
  "title_text": "Guidelines on the diagnosis and management of perioperative immediate hypersensitivity reactions 2025",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:24Z",
  "url": "https://research.draconitic.com/paper/a96cv47q714jg",
  "venue": "Journal of Allergy and Hypersensitivity Diseases",
  "versions": []
}