{
  "abstract": "Background\n\nPrepectoral implant-based breast reconstruction after nipple-sparing mastectomy or skin-sparing mastectomy has already shown several advantages. Synthetic meshes are often used as a supportive layer to achieve satisfying and stable results. We present our data using Serasynth Mesh BR Pocket, a fully dissolvable, ready-to-use mesh pocket.Methods\n\nBetween December 2021 and August 2023, a single-center retrospective study evaluated 53 breast reconstructions (43 patients) for short-term complications. Complications were classified as major (requiring revision surgery) or minor (managed conservatively). All patients underwent nipple-sparing mastectomy or skin-sparing mastectomy followed by direct-to-implant or direct-to-expander reconstruction using Serasynth Mesh BR Pocket. The minimum follow-up was 4 weeks.Results\n\nOf 53 breasts, 44 (83%) required no further surgical intervention, with a mean follow-up of 10 months (range 1-20, mo). Major complications occurred in 9 breasts (17%), and minor complications occurred in 13 (24.5%). Implant loss (13.2%) was primarily due to necrosis (7.5%). A higher body mass index (≥27 kg/m²) and axillary lymph node excision were associated with an increased risk of complications. Notably, 41.9% of patients received adjuvant radiotherapy.Conclusions\n\nSerasynth Mesh BR Pocket demonstrates a favorable safety profile in prepectoral breast reconstruction, even in a high-risk cohort with substantial radiotherapy exposure. Outcomes are comparable to those of other synthetic meshes, with the added benefit of full resorbability. Careful patient selection, considering body mass index, soft-tissue quality, and lymph node dissection, is essential to optimize results.",
  "abstract_shown": true,
  "affiliations": [
    "From the Department of Plastic, Reconstructive and Aesthetic Surgery, Hospital of the Brothers of St. John of God, Paracelsus Medical University, Salzburg, Austria.",
    "Department of Plastic Surgery, Community Hospital Feldkirch, Feldkirch, Austria.",
    "Department of Ophthalmology and Optometry, Paracelsus Medical University Salzburg, Salzburg, Austria.",
    "Research Program Experimental Ophthalmology & Glaucoma Research, Paracelsus Medical University Salzburg, Austria."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Florian Wimmer"
    },
    {
      "affs": [
        1
      ],
      "name": "Alexander Panzirsch"
    },
    {
      "affs": [
        2,
        3
      ],
      "name": "Wolfgang Hitzl"
    },
    {
      "affs": [
        1
      ],
      "name": "Gabriel Djedovic"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/aar282f2hgjwx.bib",
  "cited_by": 0,
  "doi": "10.1097/gox.0000000000008178",
  "fulltext_url": "https://europepmc.org/articles/PMC13680911",
  "id": "aar282f2hgjwx",
  "issns": [
    "2169-7574"
  ],
  "landing_url": "https://europepmc.org/article/MED/42903288",
  "language": "eng",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2746|Breast Implant and Reconstruction"
    ]
  ],
  "openalex": "W7223012424",
  "pdf_url": "https://europepmc.org/articles/PMC13680911?pdf=render",
  "pmcid": "PMC13680911",
  "pmid": "42903288",
  "published": "2026-10-20",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/aar282f2hgjwx.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:53Z",
      "native_id": "MED:42903288",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42903288"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2746|Breast Implant and Reconstruction",
      "subfield": "surgery"
    }
  ],
  "title": "Serasynth Mesh BR Pocket in Prepectoral Direct-to-implant and Tissue-expander Breast Reconstruction: A Retrospective Single-center Analysis.",
  "title_text": "Serasynth Mesh BR Pocket in Prepectoral Direct-to-implant and Tissue-expander Breast Reconstruction: A Retrospective Single-center Analysis.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:19:53Z",
  "url": "https://research.draconitic.com/paper/aar282f2hgjwx",
  "venue": "Plastic and reconstructive surgery. Global open",
  "versions": []
}