{
  "abstract": "Loneliness, social isolation, and depression are risk factors for hallucinations in patients with dementia. However, it is unclear whether relationships between these socioemotional factors and hallucinations differ in patients with Alzheimer's disease (AD) or Lewy body dementia (LBD) compared to those with neither diagnosis. We used logistic regression models on a large sample of veterans from a memory disorders clinic with varied diagnoses to test whether loneliness, social isolation, and/or depression predicted visual hallucinations (VHs) and interacted with neurocognitive diagnosis. Depression and loneliness were associated with VHs among patients with diagnoses of AD and/or Lewy body dementia, but not in those with neither diagnosis. Social isolation did not predict hallucinations in any diagnostic group. Depression and loneliness can predict the presence of VHs, depending on the patient's underlying diagnosis. Future studies are needed to tease out causal relationships.",
  "abstract_shown": true,
  "affiliations": [
    "Center for Translational Cognitive Neuroscience VA Boston Healthcare System Boston Massachusetts USA.",
    "Boston University Alzheimer's Disease Research Center Boston Massachusetts USA.",
    "University of North Carolina School of Medicine Chapel Hill North Carolina USA."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Hannah Noah"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Kathy Y Xie"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Anthony J Goñez"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Katherine W Turk"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Brandon Frank"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Andrew E Budson"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/aave570mexkym.bib",
  "cited_by": 0,
  "doi": "10.1002/dad2.70508",
  "fulltext_url": "https://europepmc.org/articles/PMC13740365",
  "id": "aave570mexkym",
  "issns": [
    "2352-8729"
  ],
  "landing_url": "https://europepmc.org/article/MED/42996468",
  "language": "eng",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Research Article"
    ],
    [
      "openalex",
      "2805|Hallucinations in medical conditions"
    ]
  ],
  "openalex": "W7225429687",
  "pdf_url": "https://europepmc.org/articles/PMC13740365?pdf=render",
  "pmcid": "PMC13740365",
  "pmid": "42996468",
  "published": "2026-10-01",
  "publisher": "Wiley",
  "ris": "https://research.draconitic.com/paper/aave570mexkym.ris",
  "sources": [
    {
      "first_seen": "2026-11-09T15:20:41Z",
      "native_id": "MED:42996468",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42996468"
    },
    {
      "first_seen": "2026-11-10T12:21:38Z",
      "native_id": "PMC13740365",
      "source": "pmc",
      "url": "https://doi.org/10.1002/dad2.70508"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:2805|Hallucinations in medical conditions",
      "subfield": "neuroscience"
    }
  ],
  "title": "Depression and loneliness differentially predict visual hallucinations in veterans with Alzheimer's disease and Lewy body dementia.",
  "title_text": "Depression and loneliness differentially predict visual hallucinations in veterans with Alzheimer's disease and Lewy body dementia.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-10T12:21:38Z",
  "url": "https://research.draconitic.com/paper/aave570mexkym",
  "venue": "Alzheimer's & dementia (Amsterdam, Netherlands)",
  "versions": []
}