{
  "abstract": "A 65-year-old woman with a history of silicone breast implantation was admitted to our hospital with abnormal chest shadows. Although the implants had already been removed, chest CT revealed diffuse ground-glass opacities in both lungs. Thoracoscopic lung biopsy revealed non-necrotizing epithelioid granulomas and silica-phagocytic macrophages, leading to a diagnosis of silicone-implant-associated autoimmune/inflammatory syndrome induced by adjuvants (ASIA). Over a follow-up period of more than 15 years without treatment, the ground-glass opacities improved only slightly. We herein present the longest follow-up chest CT findings of silicone implant-associated ASIA.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 25,
  "authors": [
    {
      "name": "Natsumi Watanabe"
    },
    {
      "name": "Yoshinori Tanino"
    },
    {
      "name": "Takefumi Nikaido"
    },
    {
      "name": "Yuki Sato"
    },
    {
      "name": "Ryuichi Togawa"
    },
    {
      "name": "Xintao Wang"
    },
    {
      "name": "Naoko Fukuhara"
    },
    {
      "name": "Tetsuya Egawa"
    },
    {
      "name": "Takahiro Kumanaka"
    },
    {
      "name": "Ryutaro Tanaka"
    },
    {
      "name": "Kentaro Kazama"
    },
    {
      "name": "Koshi Saito"
    },
    {
      "name": "Rina Harigane"
    },
    {
      "name": "Ryuki Yamada"
    },
    {
      "name": "Riko Sato"
    },
    {
      "name": "Hikaru Tomita"
    },
    {
      "name": "Mami Rikimaru"
    },
    {
      "name": "Takashi Umeda"
    },
    {
      "name": "Yasuhito Suzuki"
    },
    {
      "name": "Junpei Saito"
    },
    {
      "name": "Kenya Kanazawa"
    },
    {
      "name": "Hiroyuki Suzuki"
    },
    {
      "name": "Yuko Hashimoto"
    },
    {
      "name": "Akira Hebisawa"
    },
    {
      "name": "Yoko Shibata"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/afhd5g77vq9qf.bib",
  "cited_by": 1,
  "doi": "10.2169/internalmedicine.5944-25",
  "fulltext_url": "https://www.jstage.jst.go.jp/article/internalmedicine/65/15/65_5944-25/_article",
  "id": "afhd5g77vq9qf",
  "issns": [
    "1349-7235",
    "0918-2918"
  ],
  "landing_url": "https://www.jstage.jst.go.jp/article/internalmedicine/65/15/65_5944-25/_article",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "jstage-journal",
      "medicine/general"
    ],
    [
      "openalex",
      "2737|Sarcoidosis and Beryllium Toxicity Research"
    ]
  ],
  "openalex": "W7118004422",
  "pdf_url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_5944-25/_pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-08-01",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/afhd5g77vq9qf.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:31Z",
      "native_id": "10.2169/internalmedicine.5944-25",
      "source": "jstage",
      "url": "https://www.jstage.jst.go.jp/article/internalmedicine/65/15/65_5944-25/_article"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2737|Sarcoidosis and Beryllium Toxicity Research",
      "subfield": "physiology"
    }
  ],
  "title": "A 15-year Follow-up of Persistent Pulmonary Lesions after Silicone Removal in a Patient with Silicon-induced Autoimmune/Inflammatory Syndrome",
  "title_text": "A 15-year Follow-up of Persistent Pulmonary Lesions after Silicone Removal in a Patient with Silicon-induced Autoimmune/Inflammatory Syndrome",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:31Z",
  "url": "https://research.draconitic.com/paper/afhd5g77vq9qf",
  "venue": "Internal Medicine",
  "versions": []
}