{
  "abstract": "Objective\n\nWe aimed to compare the outcomes of tracheal resection and anastomosis (TRA) between patients undergoing initial tracheal resection and anastomosis (iTRA) and redo tracheal resection and anastomosis (reTRA).Methods\n\nIn this retrospective cohort, we used our prospectively collected database and patients who underwent TRA between March 2000 and March 2025 were included. We excluded operations performed for tracheal tumors, multisegmental stenosis, tracheoesophageal fistula, and those lost to follow-up. 1467 patients were included, of whom 51 had a history of TRA at other centers and 34 had both iTRA and reTRA at our institution, yielding 85 reTRA and 1416 iTRA cases. To ensure a well-balanced comparison, propensity-score matching (PSM) was performed, resulting in 71 matched pairs.Results\n\nPostoperative outcomes were better after iTRA, with a greater rate of excellent outcomes (72.3% vs 58.3%, P = .005). This difference was no longer significant after PSM (odds ratio, 0.71; 95% CI, 0.38-1.32, P = .28). Failure rates were similar (10.0% vs 13.0%, P = .36) and remained similar after matching (P = 1.00). There were no significant differences in the rates of subcutaneous emphysema, wound infection, dehiscence, or required postoperative bronchoscopic dilatations. The only notable difference was a greater incidence of seroma/hematoma in reTRA before PSM (10.8% vs 5.0%, P = .01), which was not observed after PSM (10.0% vs 4.2%, P = .34).Conclusions\n\nRedo TRA is not necessarily associated with greater rates of failure or complications. Although technically more challenging, redo TRA could be performed safely with comparable outcomes to initial TRA.",
  "abstract_shown": true,
  "affiliations": [
    "Tracheal Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.",
    "Lung Transplantation Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 8,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Arman Hasanzade"
    },
    {
      "affs": [
        0
      ],
      "name": "Fariba Ghorbani"
    },
    {
      "affs": [
        0
      ],
      "name": "Amir Ali Mahboobipour"
    },
    {
      "affs": [
        1
      ],
      "name": "Salman Soleimani"
    },
    {
      "affs": [
        0
      ],
      "name": "Mahboubeh Asadi"
    },
    {
      "affs": [
        1
      ],
      "name": "Azizollah Abbasi Dezfouli"
    },
    {
      "affs": [
        0
      ],
      "name": "Nahid Jahanshahi"
    },
    {
      "affs": [
        0
      ],
      "name": "Mohammad Behgam Shadmehr"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/ag46mpj1sfkea.bib",
  "cited_by": 0,
  "doi": "10.1016/j.xjon.2026.102061",
  "fulltext_url": "https://europepmc.org/articles/PMC13711287",
  "id": "ag46mpj1sfkea",
  "issns": [
    "2666-2736"
  ],
  "landing_url": "https://europepmc.org/article/MED/42948501",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Thoracic: Trachea"
    ],
    [
      "openalex",
      "2740|Tracheal and airway disorders"
    ]
  ],
  "openalex": "W7203636599",
  "pdf_url": "https://europepmc.org/articles/PMC13711287?pdf=render",
  "pmcid": "PMC13711287",
  "pmid": "42948501",
  "published": "2026-08-17",
  "publisher": "Elsevier",
  "ris": "https://research.draconitic.com/paper/ag46mpj1sfkea.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T00:20:35Z",
      "native_id": "MED:42948501",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42948501"
    },
    {
      "first_seen": "2026-10-31T12:22:05Z",
      "native_id": "PMC13711287",
      "source": "pmc",
      "url": "https://doi.org/10.1016/j.xjon.2026.102061"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2740|Tracheal and airway disorders",
      "subfield": "general"
    }
  ],
  "title": "Outcomes of redo and initial tracheal resection and anastomosis: A 25-year experience with insights from a propensity score-matched analysis.",
  "title_text": "Outcomes of redo and initial tracheal resection and anastomosis: A 25-year experience with insights from a propensity score-matched analysis.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-31T12:22:05Z",
  "url": "https://research.draconitic.com/paper/ag46mpj1sfkea",
  "venue": "JTCVS open",
  "versions": []
}