{
  "abstract": "A Cu–H-catalyzed kinetic resolution of the parent [n]helicenols (n = 5, 6) through enantioselective dehydrogenative silylation with a secondary silane is reported. The dihydrosilane eventually employed is prochiral, thereby simultaneously establishing stereogenicity at the silicon atom as part of the resolution. The method provides highly enantioenriched helicenols and reveals a pronounced structure-selectivity relationship. Among the obtained products is a previously unknown, enantioenriched triflate-functionalized helicenol that enables further diversification through cross-coupling reactions.",
  "abstract_shown": true,
  "affiliations": [
    "Technische Universität Berlin , , Strasse des 17. Juni 115 , ,"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Lisa A. Böser",
      "orcid": "0009-0007-7528-9493"
    },
    {
      "affs": [
        0
      ],
      "name": "Arthur M. J. David",
      "orcid": "0009-0006-9529-0849"
    },
    {
      "affs": [
        0
      ],
      "name": "Elisabeth Irran",
      "orcid": "0000-0001-6098-1996"
    },
    {
      "affs": [
        0
      ],
      "name": "Martin Oestreich",
      "orcid": "0000-0002-1487-9218"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/ah6m5gq2f1vcy.bib",
  "cited_by": 0,
  "doi": "10.1021/acscentsci.6c01317",
  "fulltext_url": null,
  "id": "ah6m5gq2f1vcy",
  "issns": [
    "2374-7943",
    "2374-7951"
  ],
  "landing_url": "https://pubs.acs.org/acscii/article/doi/10.1021/acscentsci.6c01317/5445596/Enantioselective-Access-to-the-Parent-Helicenols",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1605|Axial and Atropisomeric Chirality Synthesis"
    ]
  ],
  "openalex": "W7220653119",
  "pdf_url": "https://pubs.acs.org/doi/pdf/10.1021/acscentsci.6c01317",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-06",
  "publisher": "American Chemical Society (ACS)",
  "ris": "https://research.draconitic.com/paper/ah6m5gq2f1vcy.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:18:37Z",
      "native_id": "10.1021/acscentsci.6c01317",
      "source": "crossref",
      "url": "https://pubs.acs.org/acscii/article/doi/10.1021/acscentsci.6c01317/5445596/Enantioselective-Access-to-the-Parent-Helicenols"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1605|Axial and Atropisomeric Chirality Synthesis",
      "subfield": "organic"
    }
  ],
  "title": "Enantioselective Access to the Parent Helicenols by Kinetic Resolution through Cu–H-Catalyzed Si–O Coupling",
  "title_text": "Enantioselective Access to the Parent Helicenols by Kinetic Resolution through Cu–H-Catalyzed Si–O Coupling",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:18:37Z",
  "url": "https://research.draconitic.com/paper/ah6m5gq2f1vcy",
  "venue": "ACS Central Science",
  "versions": []
}