{
  "abstract": "Candida auris is an emerging multidrug-resistant yeast capable of persistent colonisation and healthcare transmission. We evaluated the implementation and microbiological yield of an electronic health record (EHR)-integrated risk-assessment pathway for targeted admission surveillance. This retrospective observational implementation study used prospectively collected admission-screening records linked to microbiology data at a 1,000-bed tertiary hospital in Riyadh, Saudi Arabia, from January 2020 through December 2022. A seven-item nursing PowerForm assigned three points for direct transfer/admission from another hospital and one point for each of six other indicators; scores ≥3 triggered the high-risk pathway. Outcomes included screening coverage, data completeness, high-risk classification and targeted-testing yield. Admissions below threshold were not systematically tested; therefore, diagnostic sensitivity, specificity and negative predictive value were not estimable. The PowerForm was completed for 68,031 admission episodes, with 475,296/476,217 expected item responses recorded (99.81%). The EHR classified 4,082 episodes as high risk (6.00%; 95% CI, 5.82%-6.18%). All 4,082 high-risk episodes in the analytic cohort had a final linked microbiological disposition; however, the extract did not distinguish whether each disposition arose from protocolised surveillance sampling or another clinical microbiology route. Fifty-three unique patients had a first laboratory-confirmed C. auris result, giving an operational targeted-testing yield of 1.30% (95% CI, 0.99%-1.69%), or approximately 77 high-risk episodes evaluated per detected case. EHR-integrated risk assessment was feasible and concentrated score-triggered screening activity on 6% of admission episodes. Because microbiological verification was pathway-dependent, the findings describe implementation yield rather than diagnostic accuracy. Prospective multicentre validation with representative testing across risk categories is required.",
  "abstract_shown": true,
  "affiliations": [
    "College of Medicine, King Saud University, Riyadh, Saudi Arabia.",
    "Division of Infectious Diseases, Department of Internal Medicine, King Saud University Medical City, King Saud University, Riyadh, Saudi Arabia.",
    "Infection Prevention and Control Department, King Saud University Medical City, King Saud University, Riyadh, Saudi Arabia.",
    "Pediatric Infectious Diseases, Department of Pediatrics, King Saud University Medical City, King Saud University, Riyadh, Saudi Arabia.",
    "Department of Pathology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.",
    "Department of Pathology, King Saud Univerity Medical City, Riyadh, Saudi Arabia.",
    "Division of Infectious Diseases, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 14,
  "authors": [
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Fatimah Saad Alshahrani",
      "orcid": "0000-0002-4646-7488"
    },
    {
      "affs": [
        2
      ],
      "name": "Abba Amsami Elgujja",
      "orcid": "0000-0003-0476-8810"
    },
    {
      "affs": [
        0,
        3
      ],
      "name": "Sara S Alsubaie",
      "orcid": "0000-0002-3128-5921"
    },
    {
      "affs": [
        2
      ],
      "name": "Salah Ahmed Ezreqat",
      "orcid": "0000-0003-4265-2050"
    },
    {
      "affs": [
        4
      ],
      "name": "Ahmed Albarrag",
      "orcid": "0000-0002-8829-9371"
    },
    {
      "affs": [
        4
      ],
      "name": "Khalifa BinKhamis",
      "orcid": "0000-0002-5425-9531"
    },
    {
      "affs": [
        1
      ],
      "name": "Lulwa Ibrahim Alabdan",
      "orcid": "0000-0001-9746-7608"
    },
    {
      "affs": [
        2
      ],
      "name": "Marytonia Valiyavettil Antony"
    },
    {
      "affs": [
        2
      ],
      "name": "Jocelyn Cordova Caparoso"
    },
    {
      "affs": [
        2
      ],
      "name": "Samah M Adam"
    },
    {
      "affs": [
        2
      ],
      "name": "Khalid Waleed Faqihi"
    },
    {
      "affs": [
        4,
        5
      ],
      "name": "Daifallah H Alshehri"
    },
    {
      "affs": [
        4,
        5
      ],
      "name": "Ghadah A Alamoudi"
    },
    {
      "affs": [
        0,
        1,
        6
      ],
      "name": "Mazin Barry",
      "orcid": "0000-0003-2274-007X"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/aht8s6t6rk07v.bib",
  "cited_by": 0,
  "doi": "10.2147/idr.s643012",
  "fulltext_url": "https://europepmc.org/articles/PMC13715537",
  "id": "aht8s6t6rk07v",
  "issns": [
    "1178-6973"
  ],
  "landing_url": "https://europepmc.org/article/MED/42953397",
  "language": "eng",
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Original Research"
    ],
    [
      "openalex",
      "2725|Antifungal resistance and susceptibility"
    ]
  ],
  "openalex": "W7223371933",
  "pdf_url": "https://europepmc.org/articles/PMC13715537?pdf=render",
  "pmcid": "PMC13715537",
  "pmid": "42953397",
  "published": "2026-10-24",
  "publisher": "Dove Press",
  "ris": "https://research.draconitic.com/paper/aht8s6t6rk07v.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T00:20:40Z",
      "native_id": "MED:42953397",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42953397"
    },
    {
      "first_seen": "2026-11-01T12:22:49Z",
      "native_id": "PMC13715537",
      "source": "pmc",
      "url": "https://doi.org/10.2147/idr.s643012"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2725|Antifungal resistance and susceptibility",
      "subfield": "infectious-disease"
    }
  ],
  "title": "Implementation and Yield of an EHR-Integrated Risk-Assessment Pathway for Targeted Candida auris Admission Surveillance in a Saudi Tertiary Hospital.",
  "title_text": "Implementation and Yield of an EHR-Integrated Risk-Assessment Pathway for Targeted Candida auris Admission Surveillance in a Saudi Tertiary Hospital.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-01T12:22:49Z",
  "url": "https://research.draconitic.com/paper/aht8s6t6rk07v",
  "venue": "Infection and drug resistance",
  "versions": []
}