{
  "abstract": "Epithelioid hemangioendothelioma (EHE) is an ultra-rare vascular neoplasm with variable biologic behavior. Mediastinal EHE is particularly uncommon and may mimic more prevalent prevascular mediastinal tumors. We report a 52-year-old man with a 10.5 × 8.9 × 9.6 cm mixed-density left upper anterior mediastinal mass containing macroscopic fat, soft-tissue components, and coarse calcification. FDG PET/CT demonstrated mild-to-moderate uptake (SUVmax 4.8) without nodal or distant metastatic disease, and the imaging appearance favored mature teratoma. Resection demonstrated a 9.5 cm conventional EHE intimately associated with a myelolipomatous component containing extensive extramedullary hematopoiesis and metaplastic ossification. The neoplastic cells expressed endothelial markers, and RNA fusion analysis detected WWTR1::CAMTA1. Surgical margins were negative, early postoperative and abdominopelvic imaging showed no residual or metastatic disease, and multidisciplinary review recommended surveillance without adjuvant therapy. Although similar EHE-myelolipoma/extramedullary hematopoiesis associations have been reported, this case emphasizes the multimodality imaging mimic of mature teratoma and provides direct radiologic-pathologic correlation of the fat-containing, solid, and ossified components.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Radiology, University of Iowa Hospitals & Clinics, Iowa City, IA, USA.",
    "Department of Pathology, University of Iowa Hospitals & Clinics, Iowa City, IA, USA.",
    "Department of Pediatrics, University of Connecticut, Hartford, CT, USA."
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Saubhagya Dhakal"
    },
    {
      "affs": [
        0
      ],
      "name": "Paulo Savoia",
      "orcid": "0000-0002-0983-1930"
    },
    {
      "affs": [
        1
      ],
      "name": "Subhashis Mitra"
    },
    {
      "affs": [
        2
      ],
      "name": "Manisha Sharma"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/ajsdza0nt7nsh.bib",
  "cited_by": 0,
  "doi": "10.1016/j.radcr.2026.09.030",
  "fulltext_url": "https://europepmc.org/articles/PMC13682456",
  "id": "ajsdza0nt7nsh",
  "issns": [
    "1930-0433"
  ],
  "landing_url": "https://europepmc.org/article/MED/42904195",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2730|Vascular Tumors and Angiosarcomas"
    ]
  ],
  "openalex": "W7221545695",
  "pdf_url": "https://europepmc.org/articles/PMC13682456?pdf=render",
  "pmcid": "PMC13682456",
  "pmid": "42904195",
  "published": "2026-10-12",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/ajsdza0nt7nsh.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:53Z",
      "native_id": "MED:42904195",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42904195"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2730|Vascular Tumors and Angiosarcomas",
      "subfield": "oncology"
    }
  ],
  "title": "Anterior mediastinal epithelioid hemangioendothelioma associated with myelolipoma and extramedullary hematopoiesis mimicking a mature teratoma: A radiologic-pathologic correlation.",
  "title_text": "Anterior mediastinal epithelioid hemangioendothelioma associated with myelolipoma and extramedullary hematopoiesis mimicking a mature teratoma: A radiologic-pathologic correlation.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:19:53Z",
  "url": "https://research.draconitic.com/paper/ajsdza0nt7nsh",
  "venue": "Radiology case reports",
  "versions": []
}