{
  "abstract": "Background: Over half of patients with Crohn’s disease (CD) develop intestinal strictures that often require surgical resection. Endoscopic balloon dilatation (EBD) can be a potential alternative therapeutic option.\n\nMethods: This retrospective cohort study included adult patients with CD (≥18 years) who underwent EBD between January 2016 and September 2024 at two Canadian hospitals. The primary outcome was technical success. Secondary outcomes were clinical success at 6 and 12 months, hospitalization due to obstruction, and CD-related surgery. Cox proportional hazards models assessed predictors of outcomes.\n\nResults: A total of 234 patients (age: 47.6 years, males: 47.4%) were included with mean disease duration of 17.7 years and median follow-up of 61 months. A majority of the strictures (226/234) were dilated under ileocolonoscopy guidance, and 79.4% had symptoms at baseline. Most strictures were of de novo type (62.5%) and the median number of stricture dilatations was 3 (IQR: 2). Technical success was achieved in 81% (150/185). Clinical success was noted in 47.7% at 6 months. The cumulative probabilities of being hospitalization-free were 96.9% (95% CI 94.7-99.2]) at 1 year, 91.3% (95% CI 87.5-95.2) at 3 years, and 85.0% (95% CI 79.8-90.5) at 5 years. The cumulative probabilities of being surgery-free were 91.1% (95% CI 87.5-94.9) at 1 year, 81.7% (95% CI 76.5-87.2) at 3 years, and 78.1% (95% CI 72.4-84.3) at 5 years. Multiple strictures were associated with an increased risk of surgery while anastomotic strictures and maximum balloon diameter were associated with lower risk. No patients experienced procedure-related complications.\n\nConclusions: EBD is effective and safe in de novo and anastomotic strictures with the majority of patients achieving technical success and being free of surgery within 5 years.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 8,
  "authors": [
    {
      "name": "Sudheer Kumar Vuyyuru",
      "orcid": "0000-0002-8281-3237"
    },
    {
      "name": "Gaurav Nigam",
      "orcid": "0000-0003-4699-2263"
    },
    {
      "name": "Shane W Goodwin"
    },
    {
      "name": "Shivya Sethi"
    },
    {
      "name": "Jamie Gregor"
    },
    {
      "name": "Brian Yan"
    },
    {
      "name": "Michael Sey"
    },
    {
      "name": "Vipul Jairath",
      "orcid": "0000-0002-1092-0033"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/akmbrngp07k28.bib",
  "cited_by": 0,
  "doi": "10.1093/ecco-jcc/jjag172",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13735507/",
  "id": "akmbrngp07k28",
  "issns": [
    "1873-9946",
    "1876-4479"
  ],
  "landing_url": "https://doi.org/10.1093/ecco-jcc/jjag172",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "AcademicSubjects/MED00260"
    ],
    [
      "heading",
      "Original Article"
    ],
    [
      "openalex",
      "2715|Inflammatory Bowel Disease"
    ]
  ],
  "openalex": "W7225254200",
  "pdf_url": "https://academic.oup.com/ecco-jcc/article-pdf/20/10/jjag172/73040329/jjag172.pdf",
  "pmcid": "PMC13735507",
  "pmid": "42982756",
  "published": "2026-11-04",
  "publisher": "Oxford University Press",
  "ris": "https://research.draconitic.com/paper/akmbrngp07k28.ris",
  "sources": [
    {
      "first_seen": "2026-11-09T12:21:10Z",
      "native_id": "PMC13735507",
      "source": "pmc",
      "url": "https://doi.org/10.1093/ecco-jcc/jjag172"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2715|Inflammatory Bowel Disease",
      "subfield": "general"
    }
  ],
  "title": "Outcomes of endoscopic balloon dilatation for de novo and anastomotic Crohn’s strictures: a Canadian tertiary center experience",
  "title_text": "Outcomes of endoscopic balloon dilatation for de novo and anastomotic Crohn’s strictures: a Canadian tertiary center experience",
  "type": "peer-reviewed",
  "updated_at": "2026-11-09T12:21:10Z",
  "url": "https://research.draconitic.com/paper/akmbrngp07k28",
  "venue": "Journal of Crohn's & Colitis",
  "versions": []
}