{
  "abstract": "Light scattering in biological tissue limits deep optical imaging. Acoustic waves can modulate optical properties and enhance photon delivery, but source-positioning requirements can complicate integration with other imaging modalities. Here, we present an open elliptical reflector that focuses laser-induced acoustic waves at a spatially separated target while maintaining open optical access. We characterized the spatiotemporal optical modulation induced by the localized acoustic focus. The system increased the local transmitted-light intensity by a factor of 2.57-fold through a 2-mm-thick 1% intralipid hydrogel and enhanced fluorescence signal under two-photon excitation through a 1.5-mm-thick scattering sample. These results demonstrate spatially separated, reflector-based acoustically assisted light guiding for enhanced light delivery and fluorescence excitation through scattering media.",
  "abstract_shown": true,
  "affiliations": [
    "The University of Tokyo"
  ],
  "article_type": "New results",
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "name": "Y. Liu"
    },
    {
      "name": "K. Shimada"
    },
    {
      "name": "K. Kitamura"
    },
    {
      "name": "S. Barrera"
    },
    {
      "name": "M. Ye"
    },
    {
      "name": "A. Ishijima"
    },
    {
      "affs": [
        0
      ],
      "name": "K. Nakagawa"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/an08v5tzsbxkz.bib",
  "cited_by": 0,
  "doi": "10.64898/2026.09.17.752288",
  "fulltext_url": "https://www.biorxiv.org/content/10.64898/2026.09.17.752288v1.full",
  "id": "an08v5tzsbxkz",
  "issns": [],
  "landing_url": "https://www.biorxiv.org/content/10.64898/2026.09.17.752288v1",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "biorxiv",
      "bioengineering"
    ],
    [
      "openalex",
      "2204|Photoacoustic and Ultrasonic Imaging"
    ]
  ],
  "openalex": "W7213555094",
  "pdf_url": "https://www.biorxiv.org/content/10.64898/2026.09.17.752288v1.full.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-17",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/an08v5tzsbxkz.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:23:02Z",
      "native_id": "10.64898/2026.09.17.752288",
      "source": "biorxiv",
      "url": "https://www.biorxiv.org/content/10.64898/2026.09.17.752288v1"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "biorxiv:bioengineering",
      "subfield": "systems-synthetic"
    }
  ],
  "title": "Light Guiding in Scattering Media Using Focused Laser-Induced Acoustic Waves with an Open Elliptical Reflector",
  "title_text": "Light Guiding in Scattering Media Using Focused Laser-Induced Acoustic Waves with an Open Elliptical Reflector",
  "type": "preprint",
  "updated_at": "2026-10-30T12:23:02Z",
  "url": "https://research.draconitic.com/paper/an08v5tzsbxkz",
  "venue": "bioRxiv",
  "versions": []
}