{
  "abstract": "R&D is a fundamental means for driving innovation in the market, maintaining competitive advantages and ensuring long-term business and sustainability. For this purpose, it is considered necessary to find new opportunities for making novel products in the fields of cosmetics (cosmeceuticals) and diet supplements (nutraceuticals), remembering that scientific research is organized in three phases: basic, applied and industrial. After explaining the significance of these phases, this paper will discuss the physical, mental, spiritual, emotional, social, economic and environmental global conditions for trying to achieve healthy beauty together with wellness, wellbeing, wealth and longevity by the so-called Beauty from Within (BW) notion, following actual consumer demand and the cosme-nutraceutical market. According to the BW rules, in fact, to obtain real healthy beauty, it is necessary to simultaneously use the same ingredients applied on the skin surface via a cosmetic product (cosmeceutical) and taken via the oral route through a specific diet supplement (nutraceutical). For this purpose, our research group is proposing specialized tissue-carriers to be used as alternative vehicles in partial substitution of the actual emulsions. The effectiveness of these novel natural and biodegradable skin- and eco-friendly vehicles, used to load, carry and release selected active ingredients by innovative cosme-nutraceuticals, has been supported and controlled by in vitro and in vivo studies. Therefore, they might be useful for safeguarding global human health and the body’s microbiome and maintaining environmental integrity. The majority of cosmetics and diet supplements, in fact, are using various emulsions as vehicles that contain different kinds of chemicals, such as preservatives, emulsifiers, fragrances and other ingredients, which often cause skin allergies and sensitization phenomena. Moreover, the majority of these cosme-nutraceuticals are packed in non-biodegradable plastic containers, unlike our proposed products, which are packed in biodegradable paper or aluminum foil. Thus, these novel cosme-nutraceuticals, made from natural polymers and ingredients and packed in plastic-free containers, are 100% biodegradable and characterized by significant effectiveness and safety. Moreover, this category of cosmetics seems capable of supporting cell adhesion, proliferation and differentiation, reinforcing their intercommunication, increasing ECM activity, maintaining AMP activity, and reducing the onset of the reported irritative phenomena, thus safeguarding the environmental microbiome’s integrity and the Earth’s biodiversity. This statement was supported by different in vitro and in vivo studies regarding both the ingredients and packaging used.",
  "abstract_shown": true,
  "affiliations": [
    "R&D Center, Nanotechnology Unit, Academy of History of Healthcare Art, 00193 Rome, Italy",
    "Shenyang and Key Laboratory of Immunodermatology, Dermatology Department, The First Hospital, China Medical University, Ministry of Health, Shenyang 110001, China",
    "Institute of Macromolecular Compounds, Russian Academy of Sciences, Sant Petersburg 199004, Russia",
    "Dermatology Department, The First Hospital, China Medical University, Shenyang 110001, China"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Pierfrancesco Morganti"
    },
    {
      "affs": [
        1
      ],
      "name": "Hong-Duo Chen"
    },
    {
      "affs": [
        2
      ],
      "name": "Vladimir E. Yudin"
    },
    {
      "affs": [
        3
      ],
      "name": "Xinghua Gao"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/ang6r3z82ss03.bib",
  "cited_by": 0,
  "doi": "10.3390/cosmetics13050262",
  "fulltext_url": "https://www.mdpi.com/2079-9284/13/5/262",
  "id": "ang6r3z82ss03",
  "issns": [
    "2079-9284"
  ],
  "landing_url": "https://doi.org/10.3390/cosmetics13050262",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "QD1-999"
    ],
    [
      "openalex",
      "3003|Advancements in Transdermal Drug Delivery"
    ]
  ],
  "openalex": "W7215037035",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-26",
  "publisher": "MDPI AG",
  "ris": "https://research.draconitic.com/paper/ang6r3z82ss03.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T14:21:26Z",
      "native_id": "04d3b998caa24703b091e63279366cdc",
      "source": "doaj",
      "url": "https://doi.org/10.3390/cosmetics13050262"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:3003|Advancements in Transdermal Drug Delivery",
      "subfield": "pharmacology-toxicology"
    }
  ],
  "title": "R&D and Innovation to Drive Healthy Beauty, Wellness, Wellbeing, Wealth and Longevity: The Novel Tissue-Carriers",
  "title_text": "R&D and Innovation to Drive Healthy Beauty, Wellness, Wellbeing, Wealth and Longevity: The Novel Tissue-Carriers",
  "type": "peer-reviewed",
  "updated_at": "2026-10-31T14:21:26Z",
  "url": "https://research.draconitic.com/paper/ang6r3z82ss03",
  "venue": "Cosmetics",
  "versions": []
}