{
  "abstract": "BackgroundAcute pulmonary embolism (PE) is a major cause of cardiovascular morbidity and mortality. This study aims to describe the epidemiological trends, clinical complexity, and in-hospital mortality of PE admissions in Spain from 2022 to 2024.\n\nMethodsWe conducted a nationwide, retrospective study using the Spanish Minimum Basic Data Set for Hospitalization (MBDS-H) for adult patients admitted with acute PE.\n\nResultsWe identified 125,305 hospital admissions for acute PE. The median patient age was 74 years with a slight male predominance (51-52%). A high comorbidity burden was observed: 61-62% had COPD, 35-37% hypertension, and 21-24% malignancy; ICU admissions increased from 11% to 13% (p < 0.001), with median ICU stay rising from 4 to 7 days (p < 0.001). In-hospital mortality significantly decreased during 2022-2024 from 13.12% to 11.44% (p = 0.013). Mortality per 100,000 inhabitants was consistently higher in men.\n\nConclusionThis study highlights the high healthcare burden posed by acute embolism in hospitals, demonstrating an increase in patient complexity alongside a decline in overall mortality.",
  "abstract_shown": true,
  "affiliations": [
    "Hospital Universitario Severo Ochoa (Madrid, Spain)"
  ],
  "article_type": "PUBLISHAHEADOFPRINT",
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "I. Mendo-Pedrajas"
    },
    {
      "name": "P. Rondon-Fernandez"
    },
    {
      "name": "C. de-Juan-Alvarez"
    },
    {
      "name": "S. Coronado-Fernandez"
    },
    {
      "name": "R. Garcia-Carretero"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/apanp03jg13qp.bib",
  "cited_by": 0,
  "doi": "10.64898/2026.09.03.26362157",
  "fulltext_url": "https://www.medrxiv.org/content/10.64898/2026.09.03.26362157v1.full",
  "id": "apanp03jg13qp",
  "issns": [],
  "landing_url": "https://www.medrxiv.org/content/10.64898/2026.09.03.26362157v1",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "medrxiv",
      "respiratory medicine"
    ],
    [
      "openalex",
      "2724|Venous Thromboembolism Diagnosis and Management"
    ]
  ],
  "openalex": "W7211938380",
  "pdf_url": "https://www.medrxiv.org/content/10.64898/2026.09.03.26362157v1.full.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-03",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/apanp03jg13qp.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:18:00Z",
      "native_id": "10.64898/2026.09.03.26362157",
      "source": "medrxiv",
      "url": "https://www.medrxiv.org/content/10.64898/2026.09.03.26362157v1"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "medrxiv:respiratory medicine",
      "subfield": "general"
    }
  ],
  "title": "Mortality and Epidemiological Characteristics of Pulmonary Embolism in Spain (2022-2024)",
  "title_text": "Mortality and Epidemiological Characteristics of Pulmonary Embolism in Spain (2022-2024)",
  "type": "preprint",
  "updated_at": "2026-10-30T12:18:00Z",
  "url": "https://research.draconitic.com/paper/apanp03jg13qp",
  "venue": "medRxiv",
  "versions": []
}