{
  "abstract": "Integrating genomic medicine into healthcare systems is a health policy challenge that requires continuously transferring scientific advances into clinics and ensuring equal access for patients. France was one of the first countries to integrate genome sequencing into clinical practice at a nationwide level, with the ambition to provide more accurate diagnostics and personalized treatments. Since 2016, the French government has invested €239M in the 2025 French Genomic Medicine Initiative (PFMG2025) which has so far focused on patients with rare diseases (RD), cancer genetic predisposition (CGP) and cancers. PFMG2025 has addressed numerous challenges to set up an operational organizational framework. As of December the 31st 2023, 12,737 results were returned to prescribers for RD/CGP patients (median delivery time: 202 days, diagnostic yield: 30.6%) and 3109 for cancer patients (median delivery time: 45 days). PFMG2025's future priorities encompass ensuring economic sustainability, strengthening links with research, empowering patients and practitioners, and fostering collaborations with European partners. Funding: As of December the 31st 2023, €239M have been invested by the French government.",
  "abstract_shown": true,
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  "article_type": null,
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  "author_total": 1090,
  "authors": [
    {
      "name": "Caroline Abadie"
    },
    {
      "name": "Aldja Abderrahmane"
    },
    {
      "name": "Ouarda Abdous"
    },
    {
      "name": "Carine Abel"
    },
    {
      "name": "Oanez Ackermann"
    },
    {
      "name": "Cécile Acquaviva"
    },
    {
      "name": "Flavie Ader"
    },
    {
      "name": "Salma Adham"
    },
    {
      "name": "Dalila Adjaoud"
    },
    {
      "name": "Alexandra Afenjar"
    },
    {
      "name": "Nathalie Aladjidi"
    },
    {
      "name": "Anne-Sophie Alary"
    },
    {
      "name": "Frédérique Albarel"
    },
    {
      "name": "Sabrina Albert"
    },
    {
      "name": "Lise Allard"
    },
    {
      "name": "Ingrid Allix"
    },
    {
      "name": "Violaine Alunni"
    },
    {
      "name": "Inês Amado"
    },
    {
      "name": "Cyril Amouroux"
    },
    {
      "name": "Nicolas André"
    },
    {
      "name": "Chloé Angelini"
    },
    {
      "name": "Mathieu Anheim"
    },
    {
      "name": "Ignacio Antolin Sanfelliz"
    },
    {
      "name": "Thomas Aparicio"
    },
    {
      "name": "Chloé Arfeuille"
    },
    {
      "name": "Jean-Benoît Arlet"
    },
    {
      "name": "Lionel Arnaud"
    },
    {
      "name": "Pauline Arnaud"
    },
    {
      "name": "Guilhem Arnold"
    },
    {
      "name": "Tania Attie-Bitach"
    },
    {
      "name": "Marion Aubert-Mucca"
    },
    {
      "name": "Isabelle Audo"
    },
    {
      "name": "Marie-Pierre Audrezet"
    },
    {
      "name": "Maxime Auroux"
    },
    {
      "name": "Céline Auzanneau"
    },
    {
      "name": "Xavier Ayrignac"
    },
    {
      "name": "Ibrahima Ba"
    },
    {
      "name": "Anne Bachelot"
    },
    {
      "name": "Delphine Bacq"
    },
    {
      "name": "Séverine Bacrot"
    },
    {
      "name": "Brigitte Bader-Meunier"
    },
    {
      "name": "Sarah Baer"
    },
    {
      "name": "Stéphanie Baert-Desurmont"
    },
    {
      "name": "Laurence Bal-Theoleyre"
    },
    {
      "name": "Ralyath Balogoun"
    },
    {
      "name": "Philippe Baltzinger"
    },
    {
      "name": "Guillaume Banneau"
    },
    {
      "name": "Claire Bar"
    },
    {
      "name": "Audrey Barbet"
    },
    {
      "name": "Giulia Barcia"
    },
    {
      "name": "Laure Barjhoux"
    },
    {
      "name": "Anne Barlier"
    },
    {
      "name": "Vincent Barlogis"
    },
    {
      "name": "Marc Barritault"
    },
    {
      "name": "Magalie Barth"
    },
    {
      "name": "Aurore Barthod-Malat"
    },
    {
      "name": "Peggy Baudouin-Cornu"
    },
    {
      "name": "Geneviève Baujat"
    },
    {
      "name": "Amandine Baurand"
    },
    {
      "name": "Jacques-Olivier Bay"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/apwnfkmfpp9h9.bib",
  "cited_by": 58,
  "doi": "10.1016/j.lanepe.2024.101183",
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  "id": "apwnfkmfpp9h9",
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    "2666-7762"
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  "landing_url": "https://hal.science/hal-05788852v1",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
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      "openalex",
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  "pdf_url": "http://www.thelancet.com/article/S2666776224003521/pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-09",
  "publisher": "Elsevier",
  "ris": "https://research.draconitic.com/paper/apwnfkmfpp9h9.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:52Z",
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  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:1311|Genomics and Rare Diseases",
      "subfield": "genetics-genomics"
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  ],
  "title": "PFMG2025–integrating genomic medicine into the national healthcare system in France",
  "title_text": "PFMG2025–integrating genomic medicine into the national healthcare system in France",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:52Z",
  "url": "https://research.draconitic.com/paper/apwnfkmfpp9h9",
  "venue": "The Lancet Regional Health - Europe",
  "versions": []
}