{
  "abstract": "Background: Global measles vaccination programs have achieved significant reductions in measles-related mortality, with World Health Organization (WHO)-led initiatives expanding vaccine coverage to over 85% of children worldwide. Despite this progress, measles elimination remains elusive, undermined by anti-vaccine sentiment, armed conflicts, migration, refugee crises, and post-COVID-19 disruptions. No WHO region has achieved or sustained measles elimination status since the COVID-19 pandemic, and elimination remains challenging in resource-limited and conflict-affected contexts. A critical yet underappreciated consequence of this ongoing burden is the rise of post-measles complications (PMCs). Vaccine-preventable diseases and malnutrition constitute two critical global health priorities; PMCs represent an important intersection of these agendas that warrant greater attention within the global health framework.\n\nObjectives: To review and synthesize current epidemiological evidence on PMCs, examine their pathogenesis, and understand the need for integrated post-measles care strategies in vulnerable populations.\n\nMethods: This narrative review included all papers that published primary data on any of the PMCs in the last 55 years, identified through PubMed and Google Scholar.\n\nFindings: Epidemiological data show that 30–40% of measles cases in low- and middle-income countries (LMICs) develop complications, including pneumonia, diarrhea, otitis media, and, less commonly, encephalitis and ocular disease. PMCs are frequently misattributed to independent illnesses because they often emerge after a delay following the acute infection. Compounding this, measles-induced immune amnesia renders affected individuals vulnerable to secondary infections for up to 2–3 years post-infection. In LMICs and conflict-affected settings, this prolonged immunological vulnerability intersects with pre-existing risk factors such as malnutrition, micronutrient deficiencies, and poor healthcare access, which amplify the consequences substantially.\n\nConclusions: As measles cases resurge globally, the associated burden of PMCs is expected to increase correspondingly. Where PMCs represent a pressing, underaddressed concern, integrated post-measles care strategies are urgently needed from a global health perspective, especially in resource-limited and conflict-affected settings.",
  "abstract_shown": true,
  "affiliations": [
    "ICMR-National Institute of Virology, Pune, Maharashtra 411021, India",
    "ICMR- National Institute of Translational Virology and AIDS Research, Pune, Maharashtra 411026, India",
    "Armed Forces Medical College, Pune, Maharashtra 411040, India"
  ],
  "article_type": "review article",
  "arxiv": null,
  "author_total": 10,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Abhijeet V. Jadhav",
      "orcid": "0000-0002-8546-7544"
    },
    {
      "affs": [
        0
      ],
      "name": "Sankalp Ghadei"
    },
    {
      "affs": [
        0
      ],
      "name": "Sanket Sonawane"
    },
    {
      "affs": [
        0
      ],
      "name": "Pushkar Patil"
    },
    {
      "affs": [
        0
      ],
      "name": "Prashant Birajdar"
    },
    {
      "affs": [
        0
      ],
      "name": "Avinash Deoshatwar"
    },
    {
      "affs": [
        1
      ],
      "name": "Kunal Pise"
    },
    {
      "affs": [
        2
      ],
      "name": "Amol Nath"
    },
    {
      "affs": [
        0
      ],
      "name": "Shailesh Pawar"
    },
    {
      "affs": [
        0
      ],
      "name": "Naveen Kumar"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/aq3cv0peq1be4.bib",
  "cited_by": 0,
  "doi": "10.5334/aogh.5307",
  "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13722016/?tool=EBI",
  "id": "aq3cv0peq1be4",
  "issns": [
    "2214-9996"
  ],
  "landing_url": "https://europepmc.org/article/PMC/PMC13722016",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Reviews"
    ],
    [
      "openalex",
      "2713|Virology and Viral Diseases"
    ]
  ],
  "openalex": "W7223694878",
  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13722016/pdf/?tool=EBI",
  "pmcid": "PMC13722016",
  "pmid": "42965144",
  "published": "2026-10-26",
  "publisher": "Ubiquity Press",
  "ris": "https://research.draconitic.com/paper/aq3cv0peq1be4.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T12:21:36Z",
      "native_id": "PMC:PMC13722016",
      "source": "europepmc",
      "url": "https://europepmc.org/article/PMC/PMC13722016"
    },
    {
      "first_seen": "2026-11-03T12:22:36Z",
      "native_id": "PMC13722016",
      "source": "pmc",
      "url": "https://doi.org/10.5334/aogh.5307"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2713|Virology and Viral Diseases",
      "subfield": "epidemiology-public-health"
    }
  ],
  "title": "Post-Measles Complications and Mortality in Children under Five Years in Low- and Middle-Income Countries: A Narrative Review",
  "title_text": "Post-Measles Complications and Mortality in Children under Five Years in Low- and Middle-Income Countries: A Narrative Review",
  "type": "peer-reviewed",
  "updated_at": "2026-11-03T12:22:36Z",
  "url": "https://research.draconitic.com/paper/aq3cv0peq1be4",
  "venue": "Annals of global health",
  "versions": []
}