{
  "abstract": "Introduction: Deprescribing is the planned withdrawal or dose reduction of medicines when harms outweigh benefits or when they are no longer required. Following publication of the Clinical Practice Guideline for Deprescribing in Older People in September 2025, supporting its uptake into routine practice is a critical next step.\n\nAim: This study aimed to identify implementation strategies, informed by stakeholder-perceived barriers, to support the implementation of deprescribing guidelines.\n\nMethod: A qualitative analysis was undertaken of open-text responses collected during the guideline public consultation (24 April–31 May 2025). Inductive thematic analysis identified implementation barriers, which were then deductively mapped to the Consolidated Framework for Implementation Research (CFIR). Relevant CFIR constructs were entered into the CFIR-Expert Recommendations for Implementing Change (ERIC) Matching Tool to generate implementation strategies. Strategies were ranked by cumulative percentage endorsement and grouped using ERIC concept-mapping clusters.\n\nResults: Of 313 survey respondents, 248 provided responses relevant to implementation. Three barrier themes were shared across consumer and professional/policy stakeholder groups. Theme 1: ‘Knowledge gaps, beliefs, and limited readiness to deprescribe’ describes gaps in consumers’ and clinicians’ knowledge, beliefs about medication use and deprescribing, and limited confidence or willingness to engage in deprescribing. Theme 2: ‘Communication, hierarchy, or social influences limiting deprescribing’ describes communication gaps, entrenched prescribing norms, power imbalances, and social influences that limited shared decision-making. Theme 3: ‘System-level structures misaligned with deprescribing practice’ describes broader healthcare system barriers, including financial, policy, workforce, organisational, and information-related constraints. Consumers additionally highlighted a lack of person-centred and adaptable approach for deprescribing, while professional/policy stakeholders identified barriers related to medicine formulations and guideline format and usability. Barriers mapped predominantly to the CFIR Inner Setting domain. The highest-ranked implementation strategy was ‘Identify and prepare champions’, within the ‘Develop stakeholder interrelationships’ cluster.\n\nConclusion: Deprescribing barriers were largely situated within the Inner Setting domains. Recommended strategies emphasised stakeholder engagement and local champions, supporting locally led, relationship-based implementation approaches. Future work should evaluate the feasibility, acceptability, and effectiveness of these strategies in practice.\n\nSupplementary Information: The online version contains supplementary material available at https://doi.org/10.1007/s11096-026-02218-9.",
  "abstract_shown": true,
  "affiliations": [
    "Centre for Optimisation of Medicines, School of Health and Clinical Sciences, The University of Western Australia, 35 Stirling Highway, Crawley, Perth, WA 6009 Australia",
    "Department for Health and Wellbeing, Adelaide, Australia",
    "The University of Sydney, Sydney, Australia",
    "Sir Charles Gairdner Hospital, Perth, Australia",
    "The University of Western Australia, Perth, Australia",
    "Western Australian Centre for Health and Ageing, The University of Western Australia, Perth, Australia",
    "Institute for Health Research, The University of Notre Dame Australia, Fremantle, Australia",
    "Registry of Senior Australians Research Centre, South Australian Health and Medical Research Institute, Adelaide, Australia",
    "Flinders University, Adelaide, Australia",
    "Gowan & Associates Pty Ltd, Melbourne, Australia",
    "Monash University, Melbourne, Australia",
    "School of Medicine (Optometry), Deakin University, Waurn Ponds, Australia",
    "Australian Dental Association Victorian Branch, Melbourne, Australia",
    "Quality Use of Medicines and Pharmacy Research Centre, Clinical and Health Sciences, The University of South Australia, Adelaide, Australia",
    "The Royal Melbourne Hospital, Melbourne, Australia",
    "The University of Melbourne, Melbourne, Australia",
    "Victorian Aboriginal Health Service, Melbourne, Australia",
    "Southern Adelaide Local Health Network, Adelaide, Australia",
    "Royal Australian College of General Practitioners, Melbourne, Australia",
    "School of Pharmacy and Pharmaceutical Sciences, The University of Queensland, Brisbane, Australia",
    "Faculty of Health Sciences and Medicine, Bond University, Gold Coast, Australia",
    "Mater Health SEQ, South Brisbane, Australia",
    "School of Nursing and Midwifery, Edith Cowan University, Joondalup, Australia",
    "Royal Perth Hospital, Perth, Australia",
    "Centre for Education and Research on Ageing, Department of Geriatric Medicine, Concord Hospital and Concord Clinical School, Sydney, Australia",
    "Faculty of Medicine and Health, The University of Sydney, Sydney, Australia",
    "Blacktown Hospital, Sydney, Australia",
    "Consumer/Carer Representative, Perth, Australia",
    "Department of Nephrology, Monash Health, Melbourne, Australia",
    "Department of Medicine, Monash University, Melbourne, Australia",
    "Wicking Dementia Research and Training Centre, The University of Tasmania, Hobart, Australia",
    "Northern Adelaide Local Health Network, Adelaide, Australia",
    "Adelaide University, Adelaide, Australia",
    "Advanced Pharmacy Australia, Melbourne, Australia",
    "Austin Health, Better@Home Subacute Program, Melbourne, Australia",
    "Curtin Medical School and enAble Institute, Curtin University, Perth, Australia"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 28,
  "authors": [
    {
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        0
      ],
      "name": "Hui Wen Quek",
      "orcid": "0000-0003-3851-179X"
    },
    {
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        0
      ],
      "name": "Xisco Reus"
    },
    {
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      ],
      "name": "Kenneth Lee"
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        1,
        2
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      "name": "Veronika Seda"
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        3,
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      "name": "Leon Adams"
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        5,
        6
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      "name": "Osvaldo P. Almeida"
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        7,
        8
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      "name": "Gillian E. Caughey"
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    {
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        9,
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      "name": "Jennifer Gowan"
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    {
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        11
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      "name": "Kerryn Hart"
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    {
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        12
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      "name": "Andrew Heredia"
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        5
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      "name": "Anne-Marie Hill"
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        13
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      "name": "Lisa Kalisch Ellett"
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      "name": "Arduino A. Mangoni"
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      "name": "Anthony Marinucci"
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    {
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        19,
        20,
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      "name": "Treasure McGuire"
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    {
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        22,
        23
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      "name": "Nilufeur McKay"
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    {
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        24,
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      "name": "Vasi Naganathan"
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      "name": "Christopher Ng"
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      "name": "Maz Osborne"
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      "name": "Kevan R. Polkinghorne"
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    {
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      "name": "Constance D. Pond"
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      "name": "Sepehr Shakib"
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    {
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        33,
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      "name": "Angela Shiu"
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    {
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      "name": "Andrew Stafford"
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        23
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      "name": "Tim Whitmore"
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      "name": "Christopher Etherton-Beer"
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    {
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      "name": "Amy Page"
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  "bibtex": "https://research.draconitic.com/paper/aqrxg15wvhpk9.bib",
  "cited_by": 0,
  "doi": "10.1007/s11096-026-02218-9",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13731450/",
  "id": "aqrxg15wvhpk9",
  "issns": [
    "2210-7703",
    "2210-7711"
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  "landing_url": "https://doi.org/10.1007/s11096-026-02218-9",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
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  "native_subjects": [
    [
      "heading",
      "Research"
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    [
      "openalex",
      "3600|Health Policy Implementation Science"
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  "openalex": "W7207540373",
  "pdf_url": "https://link.springer.com/content/pdf/10.1007/s11096-026-02218-9.pdf",
  "pmcid": "PMC13731450",
  "pmid": "42690511",
  "published": "2026-09-03",
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  "ris": "https://research.draconitic.com/paper/aqrxg15wvhpk9.ris",
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      "url": "https://doi.org/10.1007/s11096-026-02218-9"
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  "subjects": [],
  "title": "A qualitative analysis to identify implementation strategies for a deprescribing clinical practice guideline using the CFIR-ERIC Matching Tool: perspectives from consumers and professional stakeholders",
  "title_text": "A qualitative analysis to identify implementation strategies for a deprescribing clinical practice guideline using the CFIR-ERIC Matching Tool: perspectives from consumers and professional stakeholders",
  "type": "peer-reviewed",
  "updated_at": "2026-11-08T12:21:38Z",
  "url": "https://research.draconitic.com/paper/aqrxg15wvhpk9",
  "venue": "International Journal of Clinical Pharmacy",
  "versions": []
}