{
  "abstract": "Diabetes mellitus is a prevalent non-communicable disease that adversely affects multiple dimensions of quality of life in children and adolescents. This study aimed to assess disease-specific quality of life (Ds-QoL) among children with diabetes and to identify associated demographic and clinical factors. A cross-sectional study was conducted in 2020–2021 in major paediatric diabetes clinics in Khartoum, Sudan. A total of 138 children with diabetes and their parents were recruited using systematic random sampling. Disease-specific quality of life was assessed using the Paediatric Quality of Life Inventory (PedsQL) 3.0 Diabetes Module. Demographic, clinical, and care-related variables were analysed using bivariate tests and multivariable models, including generalized linear modelling. Participants had a mean age of 11.1 ± 3.6 years; 64% were female, and 74.6% resided in urban areas. Type 1 diabetes was predominant (92.8%), and glycaemic control was poor in 92.3% of participants (mean HbA1c = 9.38 ± 2.59%). Children reported higher overall Ds-QoL scores than 2 parents (75.35 ± 12.02 vs. 70.82 ± 15.94). Significant child–parent differences were observed in diabetes symptoms (p = 0.003) and worry (p < 0.001), while communication scores were comparable. Increasing age was associated with greater treatment burden (r = − 0.332, p < 0.001) and diabetes-related worry (r = − 0.254, p = 0.004). Sociodemographic variables were not significantly associated with overall Ds-QoL. Hospitalization, hypoglycaemia, and diabetic ketoacidosis were associated with lower child-reported Ds-QoL, whereas regular follow-up was associated with higher Ds-QoL. In multivariable analysis, hypoglycaemia (B = − 4.97, p = 0.027) and diabetic ketoacidosis (B = − 6.48, p = 0.012) independently predicted poorer child-reported Ds-QoL. At the same time, glycaemic control was the only independent predictor of parent-reported Ds-QoL (p = 0.001). Diabetes-specific quality of life in children is primarily influenced by clinical stability and acute complications rather than sociodemographic factors. Integrating child and parent perspectives and strengthening follow-up and metabolic control may improve quality-of-life outcomes.",
  "abstract_shown": true,
  "affiliations": [
    "College of Medicine, Gulf Medical University",
    "National University",
    "Department of Community Medicine, University of Khartoum. AL"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Hiba Hajomer"
    },
    {
      "affs": [
        1
      ],
      "name": "Osama Elkhidir"
    },
    {
      "affs": [
        2
      ],
      "name": "Kamil Shaaban"
    },
    {
      "affs": [
        1
      ],
      "name": "Qurashi Ali"
    },
    {
      "affs": [
        0
      ],
      "name": "Marwa Mady"
    },
    {
      "affs": [
        0
      ],
      "name": "Shatha AlSharbatti"
    },
    {
      "affs": [
        0
      ],
      "name": "Mayssah El Nayal"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/asxgh91z4gaym.bib",
  "cited_by": 0,
  "doi": "10.1038/s41598-026-62496-1",
  "fulltext_url": "https://doi.org/10.1038/s41598-026-62496-1",
  "id": "asxgh91z4gaym",
  "issns": [
    "2045-2322"
  ],
  "landing_url": "https://doi.org/10.1038/s41598-026-62496-1",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "Q"
    ],
    [
      "lcc",
      "R"
    ],
    [
      "openalex",
      "2712|Diabetes Management and Education"
    ]
  ],
  "openalex": "W7169883488",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-07-01",
  "publisher": "Nature Portfolio",
  "ris": "https://research.draconitic.com/paper/asxgh91z4gaym.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:45:56Z",
      "native_id": "2afde7186c5849c9a16fced1cfc8b7f8",
      "source": "doaj",
      "url": "https://doi.org/10.1038/s41598-026-62496-1"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2712|Diabetes Management and Education",
      "subfield": "endocrinology-metabolism"
    }
  ],
  "title": "Disease-specific quality of life and associated health outcomes among children with diabetes in Khartoum state, sudan: a cross-sectional study",
  "title_text": "Disease-specific quality of life and associated health outcomes among children with diabetes in Khartoum state, sudan: a cross-sectional study",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:45:56Z",
  "url": "https://research.draconitic.com/paper/asxgh91z4gaym",
  "venue": "Scientific Reports",
  "versions": []
}