{
  "abstract": "BACKGROUND: Transcatheter aortic valve implantation (TAVI) is an alternative to surgical aortic valve replacement in hemodialysis patients; however, contemporary outcomes and risk stratifications remain unreported. METHODS AND RESULTS: Using data from a multicenter database, this study included 2,888 patients who underwent TAVI between 2021 and 2024: 336 (11.6%) on hemodialysis and 2,552 (88.4%) not. The primary outcome was all-cause death after TAVI; the median follow-up was 527 days. Hemodialysis patients were younger, predominantly male, and had more comorbidities with higher surgical risk. Hemodialysis and non-hemodialysis patients had similar 30-day mortality (2.9% vs. 1.5%, respectively) and major procedural complications. Hemodialysis patients had 2- to 3-fold higher rates of all-cause death (14.4% vs. 6.5% at 1-year; 21.5% vs. 11.0% at 2 years), cardiovascular death, and the composite of all-cause death and heart failure hospitalization. After adjusting for confounders, hemodialysis had no significant effect on all-cause death and the composite endpoint. Body mass index, Clinical Frailty Scale, and albumin levels were associated with all-cause death in hemodialysis patients, allowing risk stratification into low-, intermediate-, and high-risk groups. CONCLUSIONS: In this study, hemodialysis patients were younger and had more comorbidities, but 30-day mortality and complications were similar to the non-hemodialysis group. Although hemodialysis patients had higher all-cause mortality, the worse outcomes in this group were attributed to comorbidities rather than the hemodialysis itself.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 13,
  "authors": [
    {
      "name": "Ryosuke Higuchi"
    },
    {
      "name": "Shuro Narui"
    },
    {
      "name": "Itaru Takamisawa"
    },
    {
      "name": "Mamoru Nanasato"
    },
    {
      "name": "Shinichiro Doi"
    },
    {
      "name": "Shinya Okazaki"
    },
    {
      "name": "Harutoshi Tamura"
    },
    {
      "name": "Masaki Ishiyama"
    },
    {
      "name": "Hiroaki Yokoyama"
    },
    {
      "name": "Motoki Fukutomi"
    },
    {
      "name": "Shuichiro Takanashi"
    },
    {
      "name": "Mike Saji"
    },
    {
      "name": "Mitsuaki Isobe"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/atw62pm9hetwq.bib",
  "cited_by": 5,
  "doi": "10.1253/circj.cj-25-0500",
  "fulltext_url": "https://www.jstage.jst.go.jp/article/circj/90/9/90_CJ-25-0500/_article",
  "id": "atw62pm9hetwq",
  "issns": [
    "1347-4820",
    "1346-9843"
  ],
  "landing_url": "https://www.jstage.jst.go.jp/article/circj/90/9/90_CJ-25-0500/_article",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "jstage-journal",
      "medicine/cardiovascular"
    ],
    [
      "openalex",
      "2705|Cardiac Valve Diseases and Treatments"
    ]
  ],
  "openalex": "W4416106057",
  "pdf_url": "https://www.jstage.jst.go.jp/article/circj/advpub/0/advpub_CJ-25-0500/_pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-08-25",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/atw62pm9hetwq.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:24Z",
      "native_id": "10.1253/circj.cj-25-0500",
      "source": "jstage",
      "url": "https://www.jstage.jst.go.jp/article/circj/90/9/90_CJ-25-0500/_article"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2705|Cardiac Valve Diseases and Treatments",
      "subfield": "cardiovascular"
    }
  ],
  "title": "Outcomes of Hemodialysis Patients Undergoing Contemporary Transcatheter Aortic Valve Implantation ― Insights From the LAPLACE-TAVI Registry ―",
  "title_text": "Outcomes of Hemodialysis Patients Undergoing Contemporary Transcatheter Aortic Valve Implantation ― Insights From the LAPLACE-TAVI Registry ―",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:24Z",
  "url": "https://research.draconitic.com/paper/atw62pm9hetwq",
  "venue": "Circulation Journal",
  "versions": []
}