{
  "abstract": "Background\n\nSleep disturbances affect 60-80% of people with Parkinson's disease (PD) and worsen quality of life. Dyskinesia is a common complication of dopaminergic therapy, yet its link to sleep quality is poorly understood.Objectives\n\nTo examine whether clinician-rated and objectively measured dyskinesia are associated with sleep quality in PD.Methods\n\nWe studied 47 people with PD (median age 68 years; 44.7% women; median disease duration 5 years). Sleep was measured with Pittsburgh Sleep Quality Index (PSQI). Dyskinesia was rated clinically (MDS-UPDRS items 4.1, 4.2) and objectively over 7 days using Parkinson's KinetiGraph (median dyskinesia score; DKS). Regression models adjusted for age, sex, motor severity, levodopa dose, and disease duration.Results\n\nAll dyskinesia measures predicted poorer sleep unadjusted. After adjusting for levodopa dose, only DKS remained significant (B = 0.18, P = 0.047). Adding disease duration attenuated this (P = 0.051).Conclusions\n\nWearable-derived dyskinesia, but not clinician-rated dyskinesia, independently predicted poorer sleep, supporting wearable monitoring in PD.",
  "abstract_shown": true,
  "affiliations": [
    "Centre for Preventive Neurology, Wolfson Institute of Population Health, Queen Mary University of London, London, UK.",
    "Department of Neurology, The Royal London Hospital, Barts Health, London, UK.",
    "Neurology Department, Homerton Healthcare NHS Foundation Trust, London, UK.",
    "Older Person's Services & GIM Special Interest in Parkinson'' Disease, Royal London Hospital, London, UK.",
    "Sleep Disorders Centre, Guy's and St Thomas' NHS Foundation Trust, London, UK.",
    "Unidad de Trastornos del Movimiento, Servicio de Neurología, Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Sevilla, Spain."
  ],
  "article_type": "brief report",
  "arxiv": null,
  "author_total": 14,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Viktoria Azoidou",
      "orcid": "0009-0003-3613-4764"
    },
    {
      "affs": [
        1
      ],
      "name": "Essa Bhadra"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Ellen Camboe",
      "orcid": "0000-0002-9756-849X"
    },
    {
      "affs": [
        0
      ],
      "name": "Kamalesh C Dey",
      "orcid": "0000-0003-3199-5410"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Alexandra Zirra"
    },
    {
      "affs": [
        2
      ],
      "name": "Kira Rowsell"
    },
    {
      "affs": [
        2
      ],
      "name": "Corrine Quah"
    },
    {
      "affs": [
        1
      ],
      "name": "Caroline Budu"
    },
    {
      "affs": [
        3
      ],
      "name": "Thomas Boyle",
      "orcid": "0009-0002-6659-2048"
    },
    {
      "affs": [
        1
      ],
      "name": "David Gallagher"
    },
    {
      "affs": [
        0
      ],
      "name": "Jonathan P Bestwick"
    },
    {
      "affs": [
        0,
        4
      ],
      "name": "Laura Pérez-Carbonell",
      "orcid": "0000-0002-1252-6742"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Alastair J Noyce",
      "orcid": "0000-0003-3027-5497"
    },
    {
      "affs": [
        0,
        2,
        5
      ],
      "name": "Cristina Simonet",
      "orcid": "0000-0002-5555-0283"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/avc06r02r9kdp.bib",
  "cited_by": 0,
  "doi": "10.1002/mdc3.70887",
  "fulltext_url": "https://europepmc.org/articles/PMC13724529",
  "id": "avc06r02r9kdp",
  "issns": [
    "2330-1619"
  ],
  "landing_url": "https://europepmc.org/article/MED/42967816",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Brief Report"
    ],
    [
      "openalex",
      "2728|Parkinson's Disease Mechanisms and Treatments"
    ]
  ],
  "openalex": "W7163201854",
  "pdf_url": "https://europepmc.org/articles/PMC13724529?pdf=render",
  "pmcid": "PMC13724529",
  "pmid": "42967816",
  "published": "2026-11-01",
  "publisher": "Wiley",
  "ris": "https://research.draconitic.com/paper/avc06r02r9kdp.ris",
  "sources": [
    {
      "first_seen": "2026-11-03T15:20:53Z",
      "native_id": "MED:42967816",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42967816"
    },
    {
      "first_seen": "2026-11-04T12:23:05Z",
      "native_id": "PMC13724529",
      "source": "pmc",
      "url": "https://doi.org/10.1002/mdc3.70887"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2728|Parkinson's Disease Mechanisms and Treatments",
      "subfield": "neurology"
    }
  ],
  "title": "Wearable Evidence Linking Dyskinesia Burden to Sleep Quality in Parkinson's Disease.",
  "title_text": "Wearable Evidence Linking Dyskinesia Burden to Sleep Quality in Parkinson's Disease.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-06T12:20:59Z",
  "url": "https://research.draconitic.com/paper/avc06r02r9kdp",
  "venue": "Movement disorders clinical practice",
  "versions": []
}