{
  "abstract": "A series of phenylalanine-derived hypervalent iodine-based macrocycles (HIMs) bearing electron donating and withdrawing substituents were prepared. The HIM associations with the anion of tetrabutylammonium chloride (TBA-Cl) were systematically investigated using binding isotherms generated via NMR spectroscopy. The association constants of the resulting I-Cl bond were found to linearly correlate with the electronic substituents via Hammett analysis. Electron-withdrawing substituents strengthened the I–Cl bond and disassembled the macrocycle more readily. In addition, the shifting of HIM carbonyl frequencies obtained by Fourier transform infrared (FTIR) spectroscopy were found to correlate with the binding affinities and provide an alternative predictive methodology to determine HIM disassembly and anion binding affinities.",
  "abstract_shown": true,
  "affiliations": [
    "School of Chemical and Biomolecular Sciences, Southern Illinois University, 1245 Lincoln Dr., Carbondale, IL, United States, 62901"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Samsul Arafin",
      "orcid": "0009-0007-7814-488X"
    },
    {
      "affs": [
        0
      ],
      "name": "Riya Krishnan",
      "orcid": "0009-0000-2107-0225"
    },
    {
      "affs": [
        0
      ],
      "name": "Maximilian S. Kersten"
    },
    {
      "affs": [
        0
      ],
      "name": "Katherine E. Helme"
    },
    {
      "affs": [
        0
      ],
      "name": "Sean D. Moran",
      "orcid": "0000-0002-3762-6520"
    },
    {
      "affs": [
        0
      ],
      "name": "Kyle N. Plunkett",
      "orcid": "0000-0002-5691-7876"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/avqv2azbspdme.bib",
  "cited_by": 0,
  "doi": "10.26434/chemrxiv.15010288/v1",
  "fulltext_url": null,
  "id": "avqv2azbspdme",
  "issns": [],
  "landing_url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15010288/v1",
  "language": null,
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1605|Supramolecular Chemistry and Complexes"
    ]
  ],
  "openalex": "W7221510810",
  "pdf_url": "https://chemrxiv.org/doi/pdf/10.26434/chemrxiv.15010288/v1",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-12",
  "publisher": "American Chemical Society (ACS)",
  "ris": "https://research.draconitic.com/paper/avqv2azbspdme.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:22Z",
      "native_id": "10.26434/chemrxiv.15010288",
      "source": "chemrxiv",
      "url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15010288/v1"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1605|Supramolecular Chemistry and Complexes",
      "subfield": "organic"
    }
  ],
  "title": "Substituent Effects on Anion Bonding and Disassembly of Hypervalent Iodine Macrocycles",
  "title_text": "Substituent Effects on Anion Bonding and Disassembly of Hypervalent Iodine Macrocycles",
  "type": "preprint",
  "updated_at": "2026-10-30T12:17:22Z",
  "url": "https://research.draconitic.com/paper/avqv2azbspdme",
  "venue": "ChemRxiv",
  "versions": []
}