{
  "abstract": "INTRODUCTION AND HYPOTHESIS: This global consensus conference was designed to define best practice for the controversial aspects of primary surgical management of uterovaginal pelvic organ prolapse (U-POP), to identify unanswered clinical questions, and to educate junior researchers on systematic review and meta-analysis methodology. METHODS: Eleven committees were created with geographically diverse representation and tasked with answering pragmatic questions specific to U-POP surgical decision making. A systematic search of MEDLINE, Embase, and ClinicalTrials.gov from 2000 through December 2025 was performed with specific search terms for each committee. Relevant abstracts and full texts were doubly screened and included articles were doubly extracted. Guided by literature, consensus statements were created and assigned high, moderate, and low levels of evidence. Statements with low levels of evidence were presented and voted upon in-person at a consensus conference, hosted by the Department of Urology at Wake Forest University School of Medicine in Winston Salem, NC, USA. RESULTS: Contributions from 154 participants (including 33 junior researchers) from 19 countries led to 29 systematic searches, screening of 51,143 abstracts and 3,869 full-text manuscripts. There were 133 consensus statements presented at the conference; 6 were supported by high-quality, 28 by moderate-quality, and 99 by low-quality or no evidence respectively, and required Delphi process consensus. Among expert opinion statements, 58 were accepted, 32 were rejected, and 9 were eligible for revision. CONCLUSIONS: A total of 92 statements are presented here to guide clinical decision making and best practices in surgical management of primary U-POP.",
  "abstract_shown": true,
  "affiliations": [
    "Division of Urogynecology and Reconstructive Pelvic Surgery, University of Louisville Health, Louisville, KY, USA",
    "Obstetrics and Gynecology, Albany Medical College, Albany, NY, USA",
    "Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Urology, Wake Forest University School of Medicine, 1 Medical Center Boulevard, Winston Salem, NC, 27101, USA",
    "Division of Urogynecology, Department of Obstetrics and Gynecology, Federal University of Sao Paulo, Sao Paulo, Brazil",
    "Department of Obstetrics and Gynecology, Monash University, Melbourne, Australia",
    "Department of Obstetrics and Gynecology, Kings College Hospital, London, UK",
    "Department of Urology, University of California, Los Angeles, CA, USA",
    "Department of Urology, University of Michigan, Ann Arbor, MI, USA",
    "Department of Obstetrics and Gynecology, University of Leuven, Louvain, Belgium",
    "Carpenter Library, Wake Forest University School of Medicine, Winston-Salem, NC, USA",
    "Gold Coast Health, Gold Coast, QLD, Australia",
    "University of Queensland, Brisbane, QLD, Australia",
    "Glickman Urologic Institute, Lerner College of Medicine, Cleveland Clinic, Cleveland, OH, USA",
    "Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, BC, Canada",
    "Department of Obstetrics, Gynecology and Reproductive Sciences, Division of Urogynecology and Reconstructive Pelvic Surgery, University of California, San Diego, San Diego, CA, USA",
    "Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA",
    "Division of Urogynecology and Reconstructive Pelvic Surgery, University of Chicago, Chicago, IL, USA",
    "Center for Urogynecology and Pelvic Health, Surya Hospital, Mumbai, India",
    "Department of Urogynecology, Government Medical College, Cama & Albless Hospital and GT Hospital, Mumbai, India",
    "Gleneagles Hospital, Mumbai, India",
    "Mitr Hospital, Kharghar, Navi Mumbai, India",
    "Griffith University School of Medicine, Queensland, Australia",
    "Department of Urogynecology, Cork University Maternity Hospital, Cork, Ireland",
    "Department of Obstetrics and Gynecology, University of Oklahoma, Norman, OK, USA",
    "Department of Obstetrics and Gynecology, Stanford University, Stanford, CA, USA",
    "Department of Obstetrics and Gynecology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada",
    "Department of Gynecologic Surgery, Lille University Hospital, Lille, France",
    "Division of Urogynecology and Reconstructive Pelvic Surgery, University of California, San Diego, San Diego, CA, USA",
    "Department of Obstetrics and Gynecology, Isala Hospital, Zwolle, The Netherlands",
    "Department of Obstetrics and Gynecology, Imelda Hospital, Bonheiden, Belgium",
    "Department of Urology, UCHealth Northern Colorado, Loveland, CO, USA",
    "Department of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem, NC, USA",
    "Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Urology, Wake Forest University School of Medicine, 1 Medical Center Boulevard, Winston Salem, NC, 27101, USA. catherine.matthews@wfusm.edu"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 31,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Ankita Gupta",
      "orcid": "0000-0002-1117-6007"
    },
    {
      "affs": [
        1
      ],
      "name": "Cara L. Grimes",
      "orcid": "0000-0001-5927-1663"
    },
    {
      "affs": [
        2
      ],
      "name": "Gopal Badlani"
    },
    {
      "affs": [
        3
      ],
      "name": "Maria Augusta Tezelli Bortolini",
      "orcid": "0000-0002-2824-5320"
    },
    {
      "affs": [
        4
      ],
      "name": "Anna Rosamilia"
    },
    {
      "affs": [
        5
      ],
      "name": "Dudley Robinson",
      "orcid": "0000-0002-4879-6672"
    },
    {
      "affs": [
        6
      ],
      "name": "Victor W. Νitti",
      "orcid": "0000-0002-1390-7053"
    },
    {
      "affs": [
        7
      ],
      "name": "Anne Pelletier Cameron",
      "orcid": "0000-0001-8414-3065"
    },
    {
      "affs": [
        8
      ],
      "name": "Jan A. Deprest",
      "orcid": "0000-0002-4920-945X"
    },
    {
      "affs": [
        9
      ],
      "name": "Amy Sisson",
      "orcid": "0000-0002-0553-4373"
    },
    {
      "affs": [
        10,
        11
      ],
      "name": "Yu Hwee Tan"
    },
    {
      "affs": [
        12
      ],
      "name": "Howard Brian Goldman",
      "orcid": "0000-0002-9782-1379"
    },
    {
      "affs": [
        13
      ],
      "name": "Geoffrey William Cundiff",
      "orcid": "0000-0002-5777-7836"
    },
    {
      "affs": [
        14,
        15
      ],
      "name": "Marianna Alperin",
      "orcid": "0000-0002-6004-1803"
    },
    {
      "affs": [
        2
      ],
      "name": "Amr Sherif El Haraki",
      "orcid": "0000-0001-8412-5967"
    },
    {
      "affs": [
        16
      ],
      "name": "Sarah Collins",
      "orcid": "0000-0002-3602-9783"
    },
    {
      "affs": [
        17,
        18,
        19,
        20
      ],
      "name": "Aparne Hegde"
    },
    {
      "affs": [
        21
      ],
      "name": "H Kyaw",
      "orcid": "0009-0006-8001-3531"
    },
    {
      "affs": [
        22
      ],
      "name": "Reut Rotem",
      "orcid": "0000-0002-4063-5911"
    },
    {
      "affs": [
        23
      ],
      "name": "Lieschen H. Quiroz",
      "orcid": "0000-0001-7503-9864"
    },
    {
      "affs": [
        24
      ],
      "name": "Eric R. Sokol",
      "orcid": "0000-0001-6954-5875"
    },
    {
      "affs": [
        25
      ],
      "name": "Erin A. Brennand",
      "orcid": "0000-0002-0500-6060"
    },
    {
      "affs": [
        2
      ],
      "name": "Katherine Woodburn"
    },
    {
      "affs": [
        26
      ],
      "name": "Marine Lallemant",
      "orcid": "0000-0002-3341-5267"
    },
    {
      "affs": [
        27
      ],
      "name": "Cecile Ferrando"
    },
    {
      "affs": [
        28
      ],
      "name": "Hugo van Eijndhoven"
    },
    {
      "affs": [
        29
      ],
      "name": "Jan Filip Baekelandt",
      "orcid": "0000-0002-8344-8622"
    },
    {
      "affs": [
        30
      ],
      "name": "Sarah E. Ashmore",
      "orcid": "0000-0001-7826-3765"
    },
    {
      "affs": [
        16
      ],
      "name": "Kimberly Sue Kenton",
      "orcid": "0000-0003-2567-2068"
    },
    {
      "affs": [
        31
      ],
      "name": "Kaidi Kang",
      "orcid": "0000-0003-0922-5727"
    },
    {
      "affs": [
        32
      ],
      "name": "Catherine A. Matthews",
      "orcid": "0009-0006-2237-6094"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/awwd1me9tsg9g.bib",
  "cited_by": 14,
  "doi": "10.1007/s00192-026-06758-6",
  "fulltext_url": null,
  "id": "awwd1me9tsg9g",
  "issns": [
    "0937-3462",
    "1433-3023"
  ],
  "landing_url": "https://doi.org/10.1007/s00192-026-06758-6",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2745|Pelvic floor disorders treatments"
    ],
    [
      "openalex",
      "2748|Pelvic floor disorders treatments"
    ]
  ],
  "openalex": "W7167088239",
  "pdf_url": "https://link.springer.com/content/pdf/10.1007/s00192-026-06758-6.pdf",
  "pmcid": null,
  "pmid": "42390580",
  "published": "2026-07-02",
  "publisher": "Springer Science+Business Media",
  "ris": "https://research.draconitic.com/paper/awwd1me9tsg9g.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:26:54Z",
      "native_id": "W7167088239",
      "source": "openalex",
      "url": "https://doi.org/10.1007/s00192-026-06758-6"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2745|Pelvic floor disorders treatments",
      "subfield": "general"
    }
  ],
  "title": "A Global Consensus Conference on Surgical Management of Primary Uterovaginal Prolapse and Lower Urinary Tract Dysfunction: Combining Evidence with Expert Opinion",
  "title_text": "A Global Consensus Conference on Surgical Management of Primary Uterovaginal Prolapse and Lower Urinary Tract Dysfunction: Combining Evidence with Expert Opinion",
  "type": "peer-reviewed",
  "updated_at": "2026-11-09T13:21:16Z",
  "url": "https://research.draconitic.com/paper/awwd1me9tsg9g",
  "venue": "International Urogynecology Journal",
  "versions": []
}