{
  "abstract": "Aging contributes to the mellow flavor of light-aroma Baijiu partly by converting pungent aldehydes into softer-smelling acetals. Their trace levels, structural similarity, and matrix interference hinder quantification and marker identification. A DFT-guided MMIPs-AG-based MSPE-GC–MS method selectively determined four acetals, achieving >90% of equilibrium adsorption within 1 min in kinetic experiments, desorption in 10 min, enrichment factors of 22.9–38.9, detection limits of 9.4–19.0 μg/L, and recoveries of 82.8–110.6%. Analysis of nine light-aroma Baijiu samples across aging periods revealed patterns. Among them, isovaleraldehyde diethyl acetal (iVDA), hexanal diethyl acetal (HxDA), and 1,1,3,3-tetraethoxypropane (TEP) increased overall with aging, with concentrations ranging from 0.39 to 4.84 mg/L; however, phenylacetaldehyde diethyl acetal (PADA) increased from 2.37 to 4.28 before declining to 1.64 mg/L. These preliminary trends, despite one sample per labeled production year, provide an exploratory link between HxDA/TEP and labeled production year, guiding future controlled longitudinal and accelerated aging validation.",
  "abstract_shown": true,
  "affiliations": [
    "Key Laboratory of Geriatric Nutrition and Health (Beijing Technology and Business University), Ministry of Education, Beijing 100048, China",
    "Key Laboratory of Brewing Molecular Engineering of China Light Industry, Beijing Technology and Business University, Beijing 100048, China",
    "Beijing Laboratory of Food Quality and Safety, Beijing Technology and Business University, Beijing 100048, China",
    "Luzhou Laojiao Co. Ltd., Luzhou 646000, China",
    "Luzhou Pinchuang Technology Co., Ltd., Luzhou 646000, China"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 9,
  "authors": [
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Ziqi Zhang"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Yiao Diao"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Jiaqi Guo"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Wenxian Li"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Baoguo Sun"
    },
    {
      "affs": [
        3,
        4
      ],
      "name": "Liqiang Zhang"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Wei Dong"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Xiaotao Sun"
    },
    {
      "affs": [
        3,
        4
      ],
      "name": "Songtao Wang"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/axnbykf6899f2.bib",
  "cited_by": 0,
  "doi": "10.1016/j.fochx.2026.104641",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13737735/",
  "id": "axnbykf6899f2",
  "issns": [
    "2590-1575"
  ],
  "landing_url": "https://doi.org/10.1016/j.fochx.2026.104641",
  "language": "en",
  "licence": "CC-BY-NC-ND-4.0",
  "licence_label": "CC BY-NC-ND 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Research Article"
    ],
    [
      "openalex",
      "1602|Analytical chemistry methods development"
    ]
  ],
  "openalex": "W7224135386",
  "pdf_url": null,
  "pmcid": "PMC13737735",
  "pmid": "42992000",
  "published": "2026-10-28",
  "publisher": "Elsevier",
  "ris": "https://research.draconitic.com/paper/axnbykf6899f2.ris",
  "sources": [
    {
      "first_seen": "2026-11-09T12:22:51Z",
      "native_id": "PMC13737735",
      "source": "pmc",
      "url": "https://doi.org/10.1016/j.fochx.2026.104641"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1602|Analytical chemistry methods development",
      "subfield": "analytical"
    }
  ],
  "title": "DFT-guided magnetic molecularly imprinted polymers for rapid and selective enrichment of diethyl acetals in Baijiu",
  "title_text": "DFT-guided magnetic molecularly imprinted polymers for rapid and selective enrichment of diethyl acetals in Baijiu",
  "type": "peer-reviewed",
  "updated_at": "2026-11-09T12:22:51Z",
  "url": "https://research.draconitic.com/paper/axnbykf6899f2",
  "venue": "Food Chemistry: X",
  "versions": []
}