{
  "abstract": "Background\n\nIncreased arterial stiffness has been linked to osteoporosis. This study evaluates Pulse Wave Velocity (PWV) as a discriminator of osteopenia and osteoporosis at the lumbar spine and femoral neck in postmenopausal women.Methods\n\nIn this cross-sectional study, arterial stiffness and bone mineral density (BMD) at the spine and femoral neck were assessed using carotid-to-femoral Pulse PWV and dual-energy x-ray absorptiometry (DXA). Eighteen premenopausal women (mean age 41.30±4.30 years) and forty-eight postmenopausal women (mean age 59.40±9.10 years) participated in the study. Osteoporosis (T-score ≤-2.5) and osteopenia (-2.5< T-score ≤-1) were defined by T-score criteria.Results\n\nPearson's correlation results showed: PWV and femoral neck BMD (r = -0.439, P = 0.002), PWV and spine BMD (r =-0.358, P = 0.012), and PWV and menopausal duration (r = 0.381, P = 0.008). PWV demonstrated significant discriminative ability for femoral neck osteopenia [b = 0.6472, Wald = 5.717, Odds ratio (OR) = 1.910, P = 0.017, Area Under Curve (AUC) = 0.704], femoral neck osteoporosis (b = 0.7206, Wald = 5.838, OR = 2.056, P = 0.016, AUC = 0.758), spine osteopenia (b = 0.8489, Wald = 5.639, OR = 2.337, P = 0.018, AUC = 0.677), and spine osteoporosis (b = 1.0829, Wald = 8.269, OR = 2.953, P = 0.004, AUC = 0.804).Conclusion\n\nPWV was inversely correlated with femoral neck and spine BMD, and positively correlated with menopausal duration. It serves as a significant discriminator of bone health, indicating increased odds of osteopenia and osteoporosis.",
  "abstract_shown": true,
  "affiliations": [
    "University \"St Kliment Ohridski\" Bitola, Clinical Hospital - Bitola, Department of Gynecology and Obstetrics, Bitola, North Macedonia.",
    "Medico - Legal Department, MedAssess, Sydney, New South Wales, Australia.",
    "University \"St Kliment Ohridski\" Bitola, Clinical Hospital - Bitola, Department of Internal medicine, Bitola, North Macedonia.",
    "Clinical Hospital - Bitola, Department of Nuclear medicine, Bitola, North Macedonia.",
    "Clinical Hospital - Bitola, Department of Surgery, Bitola, North Macedonia.",
    "Clinical Hospital - Bitola, North Macedonia, Department of Cardiology, Bitola, North Macedonia.",
    "University \"St. Kliment Ohridski\" - Bitola, Faculty of Economics -Prilep, Department of statistics, Prilep, North Macedonia.",
    "University \"St. Kliment Ohridski\" - Bitola, Faculty of Economics -Prilep, Head of the Second Cycle of Studies, Prilep, North Macedonia."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 8,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Maja Avramovska"
    },
    {
      "affs": [
        1
      ],
      "name": "Zorica Nikleski"
    },
    {
      "affs": [
        2
      ],
      "name": "Petar Avramovski"
    },
    {
      "affs": [
        3
      ],
      "name": "Liljana Todorovska"
    },
    {
      "affs": [
        4
      ],
      "name": "Stefan Talev"
    },
    {
      "affs": [
        5
      ],
      "name": "Svetlana Stefanovska"
    },
    {
      "affs": [
        6
      ],
      "name": "Kosta Sotiroski"
    },
    {
      "affs": [
        7
      ],
      "name": "Dejan Zdraveski"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/ayszr2qdsh2yv.bib",
  "cited_by": 0,
  "doi": "10.22088/cjim.17.3.622",
  "fulltext_url": "https://europepmc.org/articles/PMC13690173",
  "id": "ayszr2qdsh2yv",
  "issns": [
    "2008-6164",
    "2008-6172"
  ],
  "landing_url": "https://europepmc.org/article/MED/42924368",
  "language": "eng",
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2732|Bone health and osteoporosis research"
    ]
  ],
  "openalex": "W7216746317",
  "pdf_url": "https://europepmc.org/articles/PMC13690173?pdf=render",
  "pmcid": "PMC13690173",
  "pmid": "42924368",
  "published": "2026-09-01",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/ayszr2qdsh2yv.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:21:02Z",
      "native_id": "MED:42924368",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42924368"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2732|Bone health and osteoporosis research",
      "subfield": "surgery"
    }
  ],
  "title": "Pulse wave velocity as a non-invasive discriminative marker of bone health in postmenopausal women.",
  "title_text": "Pulse wave velocity as a non-invasive discriminative marker of bone health in postmenopausal women.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:21:02Z",
  "url": "https://research.draconitic.com/paper/ayszr2qdsh2yv",
  "venue": "Caspian journal of internal medicine",
  "versions": []
}