{
  "abstract": "In a study of oral linezolid among 18 patients with early syphilis, 15 showed adequate serological response by 6 months. Among 6 patients treated with benzathine penicillin G, 5 showed adequate serological response. There were no serious adverse events. Linezolid shows promise for the treatment of early syphilis.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": "brief report",
  "arxiv": null,
  "author_total": 17,
  "authors": [
    {
      "name": "Ryan M Nguyen"
    },
    {
      "name": "Chrysovalantis Stafylis",
      "orcid": "0000-0002-1486-1130"
    },
    {
      "name": "Kelika A Konda"
    },
    {
      "name": "E Michael Reyes-Diaz",
      "orcid": "0000-0003-0202-2572"
    },
    {
      "name": "Kori Keith"
    },
    {
      "name": "Keith Stokes"
    },
    {
      "name": "Catherine Creticos"
    },
    {
      "name": "Candice J McNeil",
      "orcid": "0000-0003-0566-9515"
    },
    {
      "name": "Philip A Chan",
      "orcid": "0000-0003-0964-5895"
    },
    {
      "name": "James B Brock"
    },
    {
      "name": "Byron Buck"
    },
    {
      "name": "Ebony Warren"
    },
    {
      "name": "Rica M Abbott",
      "orcid": "0009-0008-1579-7506"
    },
    {
      "name": "Jennifer L Nall"
    },
    {
      "name": "Peter Salhaney"
    },
    {
      "name": "Takila Keys"
    },
    {
      "name": "Jeffrey D Klausner"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/azk4cmfgqpsqb.bib",
  "cited_by": 0,
  "doi": "10.1093/ofid/ofag690",
  "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13728569/?tool=EBI",
  "id": "azk4cmfgqpsqb",
  "issns": [
    "2328-8957"
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  "landing_url": "https://europepmc.org/article/PMC/PMC13728569",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
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  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "AcademicSubjects/MED00290"
    ],
    [
      "heading",
      "Brief Report"
    ],
    [
      "heading",
      "Clinical Trials and Therapeutics"
    ],
    [
      "openalex",
      "2725|Syphilis Diagnosis and Treatment"
    ]
  ],
  "openalex": "W7223469600",
  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13728569/pdf/?tool=EBI",
  "pmcid": "PMC13728569",
  "pmid": "42979127",
  "published": "2026-10-24",
  "publisher": "Oxford University Press",
  "ris": "https://research.draconitic.com/paper/azk4cmfgqpsqb.ris",
  "sources": [
    {
      "first_seen": "2026-11-04T15:20:46Z",
      "native_id": "PMC:PMC13728569",
      "source": "europepmc",
      "url": "https://europepmc.org/article/PMC/PMC13728569"
    },
    {
      "first_seen": "2026-11-07T12:21:31Z",
      "native_id": "PMC13728569",
      "source": "pmc",
      "url": "https://doi.org/10.1093/ofid/ofag690"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2725|Syphilis Diagnosis and Treatment",
      "subfield": "infectious-disease"
    }
  ],
  "title": "A Pilot Study of Linezolid for Early Syphilis Treatment",
  "title_text": "A Pilot Study of Linezolid for Early Syphilis Treatment",
  "type": "peer-reviewed",
  "updated_at": "2026-11-07T12:21:31Z",
  "url": "https://research.draconitic.com/paper/azk4cmfgqpsqb",
  "venue": "Open forum infectious diseases",
  "versions": []
}